Deciding life is without meaning:
Personally i think a state whrn one decides life has no meaning is when issues affecting somebody are so many that one thinks the burden is so heavy that life loses meaning and one prefers to die instead of continued suffering
Would life be less worth living?
Life becomes less worth living when one sees no future in ones life, this situation can be caused by issues affecting somebody or an attack by uncurable disease, for example the first years when AIDS was reported there were cases of people commiting suicide on the understanding that they cannot be cured.
Are sins and suffering casually connected?
Sins are not casually connected to suffering because a sin is to go against the laid down rules willingly.
suffering is hardship which may not be due to willingness but due to other calamities which are behold ones control
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