Genetics research paper

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Wvan01

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CUNY Borough of Manhattan Community College

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Topic: Ebola virus(one or two of the genes/ proteins)

1600-2000 words; double space; font 12-14(this is palatino 12); page should be numbered

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10:21 AM Wed Nov 28 89% < mail-attachment.googleusercontent.com Ć + Ask a new question - Studyp... Gmail s 3,024x4,032 pixels Gmail Min Jin't Non als t ed Takay MC Plat O men Acc CrossMark Finding Topics for your Research Paper 1) Body of paper (not including title page and references) should be at least 1400 words long. aim for 1600-2000 words, not including references the text should be double-spaced, font 12-14 (this is Palatino 12) The pages should be numbered! 2) The subject matter has to be related to genetics and/or molecular biology 3) Go for depth rather than breadth. For example, if you want to write about mitochondrial diseases, instead of listing all the diseases and giving one paragraph of information about each, select one of them and go into detail Give as much genetics-related information as possible about the disease, such as cause: what genes are implicated (concentrate on one if there is enough info), location and structure of these genes (chromosomal locations, introns, exons) is the disease caused by a mutation? identify the mutation/ most important mutations • is it a deletion, duplication, point mutation, etc is it an error in a structural gene, or a regulatory sequence? does it involve a protein? • Is it a splicing error? What is the normal function of this protein? Where is the normal cellular location of this protein? How does the mutation change the protein? avo Are there any gene therapies? (do NOT describe in detail clinical interventions, such as physical therapy) Is it an epigenetic condition? o Describe the epigenetic change, location, etc. . 5) Showcase ONE gene and its protein. Make sure that within your paper, you give detailed information about the structure and function of at least one gene and the protein it codes for. If your topic happens to be about a non-coding DNA or RNA sequence (enhancers, XIST, IncRNAs, etc), there are still always proteins that interact with those sequences, focus on one of them. Work this information into your story. 4) Go beyond the book. In other words, take the level of detail and complexity that you provide beyond that of our genetics textbook. 5) Use at least two research articles as a focus for discussion and analysis, but also provide background information from other sources. Your genetics 10:21 AM Wed Nov 28 89% < mail-attachment.googleusercontent.com Ć Ask a new question -.. -... Gmail s 3,024x4,032 pixels s 3,024x4,032 pixels Gmail articles you are analyzing will provide more background sources. Do not use textbook can be one source of background information. The reference list of the popular magazines such as Discover, Scientific American or Time as your primary article sources (go beyond this level). They are acceptable, however, as a background or secondary source. Your paper should be a review of a narrow topic. 6) Do not copy whole phrases or sentences from your sources. Do not rephrase sentence by sentence. Read a passage or a page, and take notes . Write down the ideas, presenting them in a different order. Do not follow the flow of ideas from your source(s). Express the information in your own words, combining information from different sources, and attributing each source. Take notes on the main points of each reference, and then organize those notes logically. Then flesh out your notes, and write your review, incorporating information from various sources, with your own analysis and commentary, giving appropriate attribution. Do not follow the structure or flow of ideas from any one source. Make sure everything you write is expressed in your own words. 7) List all sources, including background sources in a reference section. 8) Here are two web sites for suitable, free research and review articles: PubMed Central, and the Public Library of Science (PLOS). To get to PubMed Central: Go to the National Center for Biotechnology Information (NCBI) homepage: www.ncbi.nlm.nih.gov From the main page, select PubMed Central from the right side. As of November 2018 there were 5.1 million free articles in PubMed Central. Take the tutorial, browse around and you will probably find lots of articles on your selected topic. If not, select from among the topics represented. There should be at least a few articles you can use among 5.1 million. Look for a review about your topic. In NCBI you will also find information about gene structure, protein structure, etc. Another source of high-quality articles is the Public Library of Science series of journals. You can find them at www.plos.org. The topics you are looking for are molecular genetics topics. You don't want epidemiological, clinical, or public health studies. If you are in doubt about the suitability of an article, please show it to me. 10:22 AM Wed Nov 28 89% < mail-attachment.googleusercontent.com Ć Ask a new question -.. -... Gmail s 3,024x4,032 pixels s 3,024x4,032 pixels Gmail articles you are analyzing will provide more background sources. Do not use textbook can be one source of background information. The reference list of the popular magazines such as Discover, Scientific American or Time as your primary article sources (go beyond this level). They are acceptable, however, as a background or secondary source. Your paper should be a review of a narrow topic. 6) Do not copy whole phrases or sentences from your sources. Do not rephrase sentence by sentence. Read a passage or a page, and take notes . Write down the ideas, presenting them in a different order. Do not follow the flow of ideas from your source(s). Express the information in your own words, combining information from different sources, and attributing each source. Take notes on the main points of each reference, and then organize those notes logically. Then flesh out your notes, and write your review, incorporating information from various sources, with your own analysis and commentary, giving appropriate attribution. Do not follow the structure or flow of ideas from any one source. Make sure everything you write is expressed in your own words. 7) List all sources, including background sources in a reference section. 8) Here are two web sites for suitable, free research and review articles: PubMed Central, and the Public Library of Science (PLOS). To get to PubMed Central: Go to the National Center for Biotechnology Information (NCBI) homepage: www.ncbi.nlm.nih.gov From the main page, select PubMed Central from the right side. As of November 2018 there were 5.1 million free articles in PubMed Central. Take the tutorial, browse around and you will probably find lots of articles on your selected topic. If not, select from among the topics represented. There should be at least a few articles you can use among 5.1 million. Look for a review about your topic. In NCBI you will also find information about gene structure, protein structure, etc. Another source of high-quality articles is the Public Library of Science series of journals. You can find them at www.plos.org. The topics you are looking for are molecular genetics topics. You don't want epidemiological, clinical, or public health studies. If you are in doubt about the suitability of an article, please show it to me. 10:22 AM Wed Nov 28 © 89% < mail-attachment.googleusercontent.com & Ask a new questi... Gmail s 3,024x4,03... s 3,024x4,032 pi... s 3,024x4,032 pi... Gmail eve' fla -gro Topic Suggestions for Bio 240 Research Paper In general, concentrate on genetic aspects, not clinical. Gene expression: transcription, translation, transcription factors, promoters, mutations, gene- protein interactions, protein structure. You should go into more detail than that offered in the textbook. If you choose a parasitic organism, find information about the genes and proteins needed to establish infection, and/or about the genetics of the organism itself. You don't have to limit yourself to the topics of this list. It just has some suggestions, in case you are having trouble selecting a topic. Each hyperlink leads to a sample article related to that topic. 5 alpha reductase deficiency Achondroplasia androgen insensitivity Alzheimer's Apicomplexan parasites (Plasmodium), genetics of the apicoplast Bacillus anthracis Bacillus thuringiensis (used for genetic modification of crops) Bacterial rhodopsins (genes, functions, proteins) Black Plague Centromeres (structure, function, comparisons) Chromosomal Fusion and Speciation (ex. Human chromosome #2) Chromatin Organization, Enhancers, Insulators Chronic myelogenous leukemia (and related cancers, genetic aspects) Color vision and color blindness, retinitis pigmentosa (opsins, rhodopsins) Comparison of transcription in prokaryotes and eukaryotes Control of latency in herpesviruses (circular genomes in nervous tissue, what genes are expressed prior to an outbreak) Control of nuclear membrane disintegration during mitosis OOD Control of sex change in schooling fish (what genes get activated) CRISPR CTCF protein (insulator-binding protein, controls chromatin condensation, many functions) Cystic fibrosis Cytoplasmic inheritance Diphtheria (effects on protein synthesis, ribosome inactivation, phage infection) Ebola virus (one or two of the genes / proteins) Effects of antibiotics on bacterial protein synthesis Endosymbiosis, chloroplast, plastid or mitochondrial evolution (lots of interesting topics ) Enhancers (or a specific enhancer, and its interactions with proteins, eRNAs) Fragile X Syndrome Fungal sRNA (RNA interference used to suppress plant immunity) Genomic imprinting Her oncogene and relation to esophageal adenocarcinoma 89% O Gmail + Bio 240 Grading Rubric for Research Paper s 3,024x4,... O Background 10% s 3,024x4.... s 3,024x4,... Title 5% O mail-attachment.googleusercontent.com s 3,024x4,... Poor Fair Good Excellent Gives basically no Gives all necessary Gives pertinent information, Gives some background background but leaves out some needed information with no information, or information, but it is info, or gives some excess and no missing information that is no unneeded information information 9-10 pts. incomplete, or not relevant to genetics 7-8 pts totally relevant 5-6 points 2-4 points Paper has no title, Paper has relevant title. Paper has Paper has relevant title uninformative title like File name is cryptic. File name is (abbreviated) (your topic), but File name paper title plus your is uninformative. Examples: "Research paper", initials 5 pts "genetics”, or “research "Genetics”, etc. O points paper" 0-3 3 pts File name uninformative as well 1-2 points The molecular genetics The topic is explained, but a Information is Information presente topic is neatly explained few minor questions are not presented in an is not relevant to and well-defined. All ends answered. The information unorganized manner, genetics, or too are tied, paper is well- is divided into sections, but and is a bit disjointed. general. The topic is organized, divided into the organization is not Some repetition of sections. Information is mostly clinical or optimal. information, sections presented logically from 25-36 points statistical, with not one section to the next are not clearly defined. much molecular without unnecessary Paper is too simplistic, genetics. Paper over repetition. not enough molecular simplistic. Paper is sufficiently genetics. Information is complex for an 16-24 points presented in one long paragraph, going bac Body 40% X s 3,024... Gmail พา 10:22 AM Wed Nov 28 Ask a new... <
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