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use of anabolic steroid(AAS )suppresses the
hypothalamic-pituitary-testicular (HPT) axis thus when a “cycle” of AAS is stopped, male
users will often become temporarily hypogonadal. Although HPT function usually
recovers spontaneously within a few weeks to a few months, the authors have
encountered several men where hypogonadism persisted for more than a year after
discontinuing AAS, and several recent published reports have documented
post-AAS hypogonadism of similar duration. Persistent suppression of HPT
function may have serious clinical consequences, including infertility and
major depressive illness In addition, dysphonic feelings associated with
hypogonadism may prompt some AAS users to resume taking AAS again and again,
thus prolonging the problem of HPT suppression and leading to a syndrome of AAS
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