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The android or male pattern of fat distribution has been associated with a higher incidence of coronary artery disease. Studies have also related central abdominal obesity (indicated via increased waist-hip ratio) with increases in peripheral fasting insulin levels. It has also been associated with a change in pressor response in circulation. In response to stress in a subject with central obesity the cardiac output dependent pressor response is shifted towards a generalised rise in peripheral resistance with an associated decrease in cardiac output.
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