Thank you for the opportunity to help you with your question!Brown adipose tissue is uniquely able to rapidly produce large amounts of heat through activation of uncoupling protein (UCP) 1. Maximally stimulated brown fat can produce 300 watts/kg of heat compared to 1 watt/kg in all other tissues. UCP1 is only present in small amounts in the fetus and in precocious mammals, such as sheep and humans; it is rapidly activated around the time of birth following the substantial rise in endocrine stimulatory factors. Brown adipose tissue is then lost and/or replaced with white adipose tissue with age but may still contain small depots of beige adipocytes that have the potential to be reactivated. In humans brown adipose tissue is retained into adulthood, retains the capacity to have a significant role in energy balance, and is currently a primary target organ in obesity prevention strategies. Thermogenesis in brown fat humans is environmentally regulated and can be stimulated by cold exposure and diet, responses that may be further modulated by photoperiod. Increased understanding of the primary factors that regulate both the appearance and the disappearance of UCP1 in early life may therefore enable sustainable strategies in order to prevent excess white adipose tissue deposition through the life cycle.
That's what I have begun to tell myself whenever I catch my mind noodling around with the same thought I've had a half dozen times a day for my entire adult life: I wish I could lose a few pounds.
You see, I'm not fat and have never been more than a little overweight — the freshman 15, too much edible merriment around the holidays, that kind of thing. I'm one of those women, quite possibly like you, who worry when they've put on a couple of pounds, but who usually look perfectly fine — great, even, on a good day, depending on the spandex content of their jeans — and who stay within a healthy weight range. Yes, I exercise a lot and try to eat right, but I'm also lucky — damn lucky. Exactly how lucky, I didn't realize until I reported this story.
Please let me know if you need any clarification. I'm always happy to answer your questions.
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