Advance Pharmacology Discussion 7 Sally is a 50-year-old female who has been a jogger for several years. She has recently been diagnosed with osteoarthritis. She has been taking ibuprofen for 3 months but states that “it does not help” and hurts her stomach. The health care provider prescribes celecoxib (Celebrex) 100 mg orally twice a day. What is the first-line therapy for osteoarthritis and the mechanism of action? Sally expresses concern about all the recent news about heart problems and celecoxib (Celebrex). What information should be included in a teaching plan to help her understand about taking celecoxib and the benefits and risks? Ibuprofen and celecoxib are both nonsteroidal anti-inflammatory drugs. Explain how they are similar and different Respond to at least two of your peers by extending, refuting/correcting, or adding additional nuance to their posts. All replies must be constructive and use literature where possible. The  response Can have 200-250 words . Bibliophraphy used should be from 2016 -2021. Online Materials & Resources Schneider, M., & Krüger, K. (2013). Rheumatoid Arthritis--Early Diagnosis and Disease Management. Deutsches Aerzteblatt International, 110(27/28), 477-484. doi:10.3238/arztebl.2013.0477 Magennis, B., Lynch, T., & Corry, M. (2014). Current trends in the medical management of Parkinson's disease: implications for nursing practice. British Journal of Neuroscience Nursing, 10(2), 67-74. Larsen, M., Rosholm, J., & Hallas, J. (2014). The influence of comprehensive geriatric assessment on drug therapy in elderly patients. European Journal of Clinical Pharmacology, 70(2), 233-239. doi:10.1007/s00228-013-1601-x.