Atherosclerosis patient Case study

User Generated

ntvyf0923

Health Medical

Description

Leona is 52 years old and smokes. She is also overweight and has atherosclerosis. When she was given a 2-week vacation from work, she packed up her bags and flew from Minnesota to Sydney, Australia, for the trip she always wanted to take. Unfortunately, just 3 days after she arrived, she was hospitalized when her left calf became inflamed, causing her considerable pain. The physician attending to her told her she developed a deep vein thrombosis. (Learning Objectives: 6, 9, and 11)

  1. Explain, using your knowledge of hypercoagulability, why the trip to Australia contributed to Leona’s DVT? Why was Leona already at risk for thrombus development?
  2. How does Leona’s atherosclerosis affect platelet function? Conversely, what is the effect of increased platelet activity on the development of atherosclerosis?
  3. How do atherosclerosis and immobility promote changes in blood coagulation?
  4. When Leona was in hospital, she received heparin therapy. Explain why this course of action was taken to treat her DVT. Why was she not given heparin tablets to take back to the hotel with her?

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Running head: CASE STUDY

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Case Study
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CASE STUDY

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1. Explain, using your knowledge of hypercoagulability, why the trip to Australia
contributed to Leona’s DVT? Why was Leona already at risk for thrombus
development?
Hypercoagulability is a blood clotting disorder that increases the risk of the formation of
blood clots in a blood vessel. Hypercoagulability usually occurs in people suffering from deep
vein thrombosis as they suffer from abnormalities associated with blood coagulation. The trip to
Australia contributed immensely to Leona's deep vein thrombosis on various fronts. To this end,
various scholars of international repute have linked long-distance air travel to the development of
deep vein thrombosis in passengers. These scholars attribute this phenomenon to various aircraft
cabin factors such as low humidity, immobilization for long periods and hypobaric hypoxia.
Specifically, hypobaric hypoxia may lead to oxygen deprivation to certain body tissues, for
example in the legs, thereby predisposing an individual to deep vein thrombosis (Cannegieter,
2012). For that reason, in long fl...


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