Biochemistry questions regarding the CAC and Cori Cycle

Biology
Tutor: None Selected Time limit: 1 Day

what would happen to the amount of atp available to a cell if the entire Cori cycle were to occur and remain in a single cell?

If a hypothetical defect occurred in any enzyme in the citric acid cycle what would happen to the specific cycle products And why does atp production decrease ?

Aug 13th, 2015

Thank you for the opportunity to help you with your question!

It would drop way down, probably lethally pretty quickly. The conversion back consumes more than is liberated. (creating the lactate releases 2, moving it back to glucose consumes 6)

that is why it is primarily used in nature just for muscle movement when things have gotten a bit on the anaerobic side - the muscle can get decent ATP without having to use local oxygen and turning the lactic acid over into the Krebs cycle, with the conversion back to glucose usually taking place in the liver.

You can refer interactive website that give you basic concept of cori cycle

1) http://www.wiley.com/college/boyer/0470003790/animations/cori_cycle/cori_cycle.htm

Thanks & regards


Please let me know if you need any clarification. I'm always happy to answer your questions.
Aug 13th, 2015

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Aug 13th, 2015
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