Biochemistry questions regarding the CAC and Cori Cycle

User Generated

Pnebypunarl

Science

Description

what would happen to the amount of atp available to a cell if the entire Cori cycle were to occur and remain in a single cell?

If a hypothetical defect occurred in any enzyme in the citric acid cycle what would happen to the specific cycle products And why does atp production decrease ?

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Explanation & Answer

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It would drop way down, probably lethally pretty quickly. The conversion back consumes more than is liberated. (creating the lactate releases 2, moving it back to glucose consumes 6)

that is why it is primarily used in nature just for muscle movement when things have gotten a bit on the anaerobic side - the muscle can get decent ATP without having to use local oxygen and turning the lactic acid over into the Krebs cycle, with the conversion back to glucose usually taking place in the liver.

You can refer interactive website that give you basic concept of cori cycle

1) http://www.wiley.com/college/boyer/0470003790/animations/cori_cycle/cori_cycle.htm

Thanks & regards


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