Description
What causes Hashimoto's thyroiditis, and what is the best method of treatment? Can iodine help this condition?
User generated content is uploaded by users for the purposes of learning and should be used following Studypool's honor code & terms of service.
Explanation & Answer
Review
Review
Anonymous
I was struggling with this subject, and this helped me a ton!
Studypool
4.7
Trustpilot
4.5
Sitejabber
4.4
24/7 Homework Help
Stuck on a homework question? Our verified tutors can answer all questions, from basic math to advanced rocket science!
Most Popular Content
20 pages
Frictional Forces Data
acceleration is equal to 2y divided by t squared What happened to your applied force Fapp as you decreased the amount of w ...
Frictional Forces Data
acceleration is equal to 2y divided by t squared What happened to your applied force Fapp as you decreased the amount of water in the cup? Explain ...
5 pages
20201027010342fluids Remote Lab 1026
Please carefully read the following examples and multiple choice problems. In marking and typing in your answers, you are ...
20201027010342fluids Remote Lab 1026
Please carefully read the following examples and multiple choice problems. In marking and typing in your answers, you are expected to use bold and ...
Human Population Growth, Affluent Consumption and Environmental Impact
Human Population Growth, Affluent Consumption and Environmental Impact.Do you believe that the more “things” you want ...
Human Population Growth, Affluent Consumption and Environmental Impact
Human Population Growth, Affluent Consumption and Environmental Impact.Do you believe that the more “things” you want and possess in life makes you happier? Have you ever participated in the exercise about being stranded on a deserted island? What would you choose if you were given a list of “things” that you could have but you were only allowed to choose a limited few to survive? This is an exercise in determining what is truly “necessary” for human survival. What remains is what humans “want” to have or would like to have for whatever reason.The following assignment explores consumerism on a basic product or item level and its’ connection to human population growth and each of our ecological footprints. It can make you aware of personal consumption and how human behavior must change if the human population growth rate is to be reduced thereby shrinking our ecological footprints and conserving natural capital.PART 1Choose 2 products or items that you might find in a home or office. The products should be produced, sold and used in the United States or in a relatively affluent country. One product or item will be a simple mechanical and/or electrical device. The other product or item will NOT be mechanical or electrical. Keep it simple for example, a toaster or an automobile, and a plastic bottle or a basketball hoop.Research each product or item production, manufacture, growth or whatever process is used to make the product or item available for use. Consider in your research the cradle to grave lifespan of the product or item.For each of the two products or items, answer the following questions and provide the requested information:Is this a product or item necessary for human survival?What are the raw materials, chemicals, energy, etc. used to make the product and become part of the product or item?Is the product made from a renewable resource (ex. A tree) or a limited resource (ex. Oil)?Can the product and/or materials be recycled or reused and how?Is there any other method for reducing the materials, chemicals, energy, etc. used to make the product?Is there any alternative products or substitution for the product?Describe how the product gets from raw materials to production, manufacture, growth, etc. to the store and then to your home. What is the transportation, energy use?How is the product or item disposed of or how would it be disposed of? (even if it can be partially recycled or reused)Does it decompose to basic elements, nutrients if placed in a landfill? If yes, then how long does decomposition take?List all the negative environmental impacts of production, use and disposal of the product or item.Would you expect the production of the product or item to most likely increase as the human population increases? If yes, then what impact would you expect on the size of each person’s ecological footprint? (note: keep in mind the product or item production, sale and use is in the United States, a relatively affluent country)PART 2Write an essay that explains the environmental connections and relationship(s) among the following three topics:Human Population GrowthAffluent ConsumptionEcological FootprintThe Essay submitted as a Word document attached to the assignment tool. Your total write-up and explanation should be at least two pages with at least one page of the environmental connections and relationship(s) among the above three topics. The Essay should include the following:Answer all 11 questions from the Part 1.In Part 2, provide the reference of your essay writing using APA style.Give your creative ideas on how these articles tie into the material we are covering in class this module. See the syllabus for the assignment due date.Format the paper in your own words, and include citations and references as needed to avoid plagiarism. You can review a presentation about citation at CITATION BOOSTER.
Grossmont Cuyamaca Community College District Cystic Fibrosis Project
1. A brief introduction to the disease including the molecular basis of the disease (the membrane protein damage that cau ...
Grossmont Cuyamaca Community College District Cystic Fibrosis Project
1. A brief introduction to the disease including the molecular basis of the disease (the membrane protein damage that causes the disease), the size of the gene and the protein, the number of mutations that exist, what class mutation is the one that you are researching and what does it mean?2. The basic genetics of the disease (including the genetics describing how each parent must carry one CFTR allele in order for a child to have the disease. How many people get the disease? How is it transmitted?3. A review of the allele combinations that the child might have; you will be assigned a main allele to research in an online database, and will research in the database the three possible combinations of that allele. You will include an explanation of the potential health impact of that allele you have been assigned on the child's health (for example, impact on the lungs, pancreas, and potential for Pseudomonas infections.4. The last section should be about possible treatments. Are there new drugs (modulators) that can potentially help to deal with the particular version of CF that the child has? Or are only traditional treatment methods possible? What would those methods be? The database search will give you some information about whether The best place to find information about the drugs is on the Vertex website (link is on the database search page directions).5. The entire paper should be no longer than 4 double-spaced pages with standard 1-inch margins and a standard font no smaller than 11 points.Cystic FibrosisProject(100 points)This project is going to be a reportwhere you will beacting as a genetic counselor to the parents of a one-year-old child who has been diagnosed with Cystic Fibrosis. You will be presenting information about a particular variant (mutation) or pair of variants that cause Cystic Fibrosis. You will investigatea variant that you will be assigned, both on its own with an unknown variant on the other chromosome, or with a known common CF variant. There are a variety of web sites that have specific information about cystic fibrosis as a disease and descriptions of the etiology of the disease. The most common websites with reliable information include the following:www.vrtx.comwww.vertextreatments.comhttps://hopkinscf.org/www.cfsource.comhttps://investors.vrtx.com/news-releases/news-release-details/fda-approves-symdekor-tezacaftorivacaftor-and-ivacaftor-treatYou should read through each of these web sites and become familiar with the information contained in each one. Information in them willhelpform the basis of some of the background information for your report. You already know most of the basic information so these sites should help review what you know or add additional information to what you already know.We have reviewedin this coursehow there aresixclasses of variants to which the most common CF variants can be assigned, classes I through VI (Note: there are a few websites that will show 5 different CF mutation classes; these have older information and are missing the 6thvariant description). Information on the manner in which variants in each of these classes causes damage to the CFTR protein can be found at the following websites:https://hopkinscf.org/knowledge/cftr/#section5https://www.cff.org/What-is-CF/Genetics/Types-of-CFTR-Mutations/This website shows only 5 classes of mutations, but the graphic presented is very helpful for understanding the mutation types. The first 5 classes of mutations are the same in each case; the 6thclass is a newer variant that is not described everywhere. Investigating your VariantNow that you have investigatedsome basic information about Cystic Fibrosis, the remainder of the project will present information that is specific to the variant that youareinvestigating. What variant class does your specific variant belong to?Use the previous information you have researched to determine which class your variant belongs to. You should describe the specificmolecular problem with your variant in yourreport.2Now, go to the website at https://cftr2.org/The entry page to this website will require you to read through and answer some questions in order to get to theactualdatabase site where you can investigate your mutation. Once you get to the main page, there are threeshort videosyou can watch in order to understand the websiteand how it works. Once you have done that, you can enter data in the entry points at the top left of the page (https://cftr2.org/welcome); there are two entry points; the first says Enter first variantand the second says Second variant (optional).The goal is to research three possible combinations:1.Your assigned variant alone; since a person must have two of the genes for cystic fibrosis in order to have the disease, this search will give you information about a situation where a person has cystic fibrosis, but only one of the variants has been identified and the second is unknown. 2.Your assigned variant in both positions (this means thatthe same varianthas been determined to bepresenton both chromosomes)3.Yourassignedvariant in combination with variant F508delin the second position. Each of thesecombinationswill need to be run separately in the database and different information may be examined for each combination. You should report on each of these situations in your report. Each time you run a combination, you will be given results that you should include in your report including 1)Summary Information2)Lung Function3)% with Pancreatic Insufficiency4)Pseudomonas Infection rateCF Variant Information: As you write your report, you should includethe following:1)general background about your specific CF mutationand the class it falls into2)the information you have researched about your specific variant and the implications of the different allele combinations that you researched. 3)What class does your variant fall into? What is the problem that puts this variant into this class? What are the most common clinical manifestations for this variant?4)What percentage of the population with CF carry this variant?5)Is it possible to screen people for the presence of this variant? 6)What treatments may be available for treatment of this patient? Include traditional types of treatments and any newer CFTR modulator treatments and how they work with this variant. The following web sites contain information about testing that can be done to identify the CFTR variants in humans.3https://www.acog.org/Patients/FAQs/Cystic-Fibrosis-Prenatal-Screening-and-Diagnosis#amhttps://ltd.aruplab.com/Tests/Pdf/182https://www.labcorp.com/test-menu/23686/cystic-fibrosis-cf-profile-32-mutations-fetal-analysisPossible TreatmentsThere are many old style standard therapies to treat CF, and there are the newer CFTR Modulator treatments. Which of these treatments might be useful for patients with your gene variant?As you do your database search, there will usually be some information thatcomes up about whether any of the newer modulator treatments is possible. There are other web sites where you can find specific information if you google the specific name of one of the new modulator treatments. Otherwise you should look into some of the older, standard treatmentsfor the disease. https://www.vertextreatments.com/https://www.cff.org/Life-With-CF/Treatments-and-Therapies/Medications/CFTR-Modulator-Therapies/https://investors.vrtx.com/news-releases/news-release-details/fda-approves-symdekor-tezacaftorivacaftor-and-ivacaftor-treatCystic Fibrosis Genetic Variants1.G542X2.W1282X3.R553X4.N1303K5.I507del6.G551D7.S549N8.R117H9.R347P10.D1152H11.A455E12.2789 + 5G -ASave the paper as a Word or PDF file to submit.There are two documents that are included in this project module. 1. The first document has information that will lead you to high quality web sites that will tell you more about cystic fibrosis and help you answer the questions that need to be covered in your paper. It will also walk you through the steps to get to the database that has the information about the mutation that you will be assigned. Look at all of the directions in that document along with the information found here in order to have a complete picture of the project.2. The second document has a table that will show you which mutation you have been assigned. The list of mutations is in the far left column; you will find your name in one of the rows to the right of one of the mutations. You may NOT switch you assignment with other students in the class. The specific mutation you are researching should be included in the title of your project.The completed project is worth up to 100 points and a grading rubric will be posted in the next couple of days. The completed project is due no later than July 30th at 11:59 PM.
13 pages
An Exploration Of The Diversity Of Life Lab
For this week’s lab we will divide the lab groups up by last name. Your kingdom/domain assignment will be listed after t ...
An Exploration Of The Diversity Of Life Lab
For this week’s lab we will divide the lab groups up by last name. Your kingdom/domain assignment will be listed after the first letter of your last ...
Similar Content
Chemistry Lab Question, homework help
Chem lab question. View in attachment ...
Chemistry: what volume will 1.5 moles of oxygen gas occupy at STP?
20.0L33.6L22.4L9.02L...
Make a Cloud Jar Science Lesson Plan and Presentation
create a lesson plan with topic "Make a cloud jar". Attach will be an example of how the format should be with that ...
Principles of Human Physiology, biology homework help
this is reading assignment. its to read the chapter 12 Muscle Physiology. the book the course use is:Principles of Human P...
Chemistry Question
Element biographyWrite an informational report for the element that you chose in class (i.e. write an element biography) ...
CSU East Bay Hominids Biological Anthropology Discussion
Hypothetical: A researcher claims to have found a hominin in a South African cave site that dates to the Early Pleistocene...
Benefit Of Exercise
The topic is about defining the term MET level and how it is used by health officers. It mainly refers to the amount of en...
Electric Field And Potential
Ques 1. What is the direction of electric field of a single positive charge? Ques 2. What is the direction of electric fie...
BS105 Rasmussen Chemical & Physical Processes of Digestion Lab 8 Questions
BS105 Human Physiology Lab 8 – Chemical & Physical Processes of Digestion 1. List the substrate and the subunit product ...
Related Tags
Book Guides
The Mayor of Casterbridge
by Thomas Hardy
Death on the Nile
by Agatha Christie
Bridge to Terabithia
by Katherine Paterson
Beowulf
by Anonymous Anglo-Saxon poet
The Dispossessed
by Ursula Kroeber Le Guin
Heart of Darkness
by Joseph Conrad
Siddhartha
by Hermann Hesse
Black Beauty
by Anna Sewell
Alice in Wonderland
by Lewis Carroll
Get 24/7
Homework help
Our tutors provide high quality explanations & answers.
Post question
Most Popular Content
20 pages
Frictional Forces Data
acceleration is equal to 2y divided by t squared What happened to your applied force Fapp as you decreased the amount of w ...
Frictional Forces Data
acceleration is equal to 2y divided by t squared What happened to your applied force Fapp as you decreased the amount of water in the cup? Explain ...
5 pages
20201027010342fluids Remote Lab 1026
Please carefully read the following examples and multiple choice problems. In marking and typing in your answers, you are ...
20201027010342fluids Remote Lab 1026
Please carefully read the following examples and multiple choice problems. In marking and typing in your answers, you are expected to use bold and ...
Human Population Growth, Affluent Consumption and Environmental Impact
Human Population Growth, Affluent Consumption and Environmental Impact.Do you believe that the more “things” you want ...
Human Population Growth, Affluent Consumption and Environmental Impact
Human Population Growth, Affluent Consumption and Environmental Impact.Do you believe that the more “things” you want and possess in life makes you happier? Have you ever participated in the exercise about being stranded on a deserted island? What would you choose if you were given a list of “things” that you could have but you were only allowed to choose a limited few to survive? This is an exercise in determining what is truly “necessary” for human survival. What remains is what humans “want” to have or would like to have for whatever reason.The following assignment explores consumerism on a basic product or item level and its’ connection to human population growth and each of our ecological footprints. It can make you aware of personal consumption and how human behavior must change if the human population growth rate is to be reduced thereby shrinking our ecological footprints and conserving natural capital.PART 1Choose 2 products or items that you might find in a home or office. The products should be produced, sold and used in the United States or in a relatively affluent country. One product or item will be a simple mechanical and/or electrical device. The other product or item will NOT be mechanical or electrical. Keep it simple for example, a toaster or an automobile, and a plastic bottle or a basketball hoop.Research each product or item production, manufacture, growth or whatever process is used to make the product or item available for use. Consider in your research the cradle to grave lifespan of the product or item.For each of the two products or items, answer the following questions and provide the requested information:Is this a product or item necessary for human survival?What are the raw materials, chemicals, energy, etc. used to make the product and become part of the product or item?Is the product made from a renewable resource (ex. A tree) or a limited resource (ex. Oil)?Can the product and/or materials be recycled or reused and how?Is there any other method for reducing the materials, chemicals, energy, etc. used to make the product?Is there any alternative products or substitution for the product?Describe how the product gets from raw materials to production, manufacture, growth, etc. to the store and then to your home. What is the transportation, energy use?How is the product or item disposed of or how would it be disposed of? (even if it can be partially recycled or reused)Does it decompose to basic elements, nutrients if placed in a landfill? If yes, then how long does decomposition take?List all the negative environmental impacts of production, use and disposal of the product or item.Would you expect the production of the product or item to most likely increase as the human population increases? If yes, then what impact would you expect on the size of each person’s ecological footprint? (note: keep in mind the product or item production, sale and use is in the United States, a relatively affluent country)PART 2Write an essay that explains the environmental connections and relationship(s) among the following three topics:Human Population GrowthAffluent ConsumptionEcological FootprintThe Essay submitted as a Word document attached to the assignment tool. Your total write-up and explanation should be at least two pages with at least one page of the environmental connections and relationship(s) among the above three topics. The Essay should include the following:Answer all 11 questions from the Part 1.In Part 2, provide the reference of your essay writing using APA style.Give your creative ideas on how these articles tie into the material we are covering in class this module. See the syllabus for the assignment due date.Format the paper in your own words, and include citations and references as needed to avoid plagiarism. You can review a presentation about citation at CITATION BOOSTER.
Grossmont Cuyamaca Community College District Cystic Fibrosis Project
1. A brief introduction to the disease including the molecular basis of the disease (the membrane protein damage that cau ...
Grossmont Cuyamaca Community College District Cystic Fibrosis Project
1. A brief introduction to the disease including the molecular basis of the disease (the membrane protein damage that causes the disease), the size of the gene and the protein, the number of mutations that exist, what class mutation is the one that you are researching and what does it mean?2. The basic genetics of the disease (including the genetics describing how each parent must carry one CFTR allele in order for a child to have the disease. How many people get the disease? How is it transmitted?3. A review of the allele combinations that the child might have; you will be assigned a main allele to research in an online database, and will research in the database the three possible combinations of that allele. You will include an explanation of the potential health impact of that allele you have been assigned on the child's health (for example, impact on the lungs, pancreas, and potential for Pseudomonas infections.4. The last section should be about possible treatments. Are there new drugs (modulators) that can potentially help to deal with the particular version of CF that the child has? Or are only traditional treatment methods possible? What would those methods be? The database search will give you some information about whether The best place to find information about the drugs is on the Vertex website (link is on the database search page directions).5. The entire paper should be no longer than 4 double-spaced pages with standard 1-inch margins and a standard font no smaller than 11 points.Cystic FibrosisProject(100 points)This project is going to be a reportwhere you will beacting as a genetic counselor to the parents of a one-year-old child who has been diagnosed with Cystic Fibrosis. You will be presenting information about a particular variant (mutation) or pair of variants that cause Cystic Fibrosis. You will investigatea variant that you will be assigned, both on its own with an unknown variant on the other chromosome, or with a known common CF variant. There are a variety of web sites that have specific information about cystic fibrosis as a disease and descriptions of the etiology of the disease. The most common websites with reliable information include the following:www.vrtx.comwww.vertextreatments.comhttps://hopkinscf.org/www.cfsource.comhttps://investors.vrtx.com/news-releases/news-release-details/fda-approves-symdekor-tezacaftorivacaftor-and-ivacaftor-treatYou should read through each of these web sites and become familiar with the information contained in each one. Information in them willhelpform the basis of some of the background information for your report. You already know most of the basic information so these sites should help review what you know or add additional information to what you already know.We have reviewedin this coursehow there aresixclasses of variants to which the most common CF variants can be assigned, classes I through VI (Note: there are a few websites that will show 5 different CF mutation classes; these have older information and are missing the 6thvariant description). Information on the manner in which variants in each of these classes causes damage to the CFTR protein can be found at the following websites:https://hopkinscf.org/knowledge/cftr/#section5https://www.cff.org/What-is-CF/Genetics/Types-of-CFTR-Mutations/This website shows only 5 classes of mutations, but the graphic presented is very helpful for understanding the mutation types. The first 5 classes of mutations are the same in each case; the 6thclass is a newer variant that is not described everywhere. Investigating your VariantNow that you have investigatedsome basic information about Cystic Fibrosis, the remainder of the project will present information that is specific to the variant that youareinvestigating. What variant class does your specific variant belong to?Use the previous information you have researched to determine which class your variant belongs to. You should describe the specificmolecular problem with your variant in yourreport.2Now, go to the website at https://cftr2.org/The entry page to this website will require you to read through and answer some questions in order to get to theactualdatabase site where you can investigate your mutation. Once you get to the main page, there are threeshort videosyou can watch in order to understand the websiteand how it works. Once you have done that, you can enter data in the entry points at the top left of the page (https://cftr2.org/welcome); there are two entry points; the first says Enter first variantand the second says Second variant (optional).The goal is to research three possible combinations:1.Your assigned variant alone; since a person must have two of the genes for cystic fibrosis in order to have the disease, this search will give you information about a situation where a person has cystic fibrosis, but only one of the variants has been identified and the second is unknown. 2.Your assigned variant in both positions (this means thatthe same varianthas been determined to bepresenton both chromosomes)3.Yourassignedvariant in combination with variant F508delin the second position. Each of thesecombinationswill need to be run separately in the database and different information may be examined for each combination. You should report on each of these situations in your report. Each time you run a combination, you will be given results that you should include in your report including 1)Summary Information2)Lung Function3)% with Pancreatic Insufficiency4)Pseudomonas Infection rateCF Variant Information: As you write your report, you should includethe following:1)general background about your specific CF mutationand the class it falls into2)the information you have researched about your specific variant and the implications of the different allele combinations that you researched. 3)What class does your variant fall into? What is the problem that puts this variant into this class? What are the most common clinical manifestations for this variant?4)What percentage of the population with CF carry this variant?5)Is it possible to screen people for the presence of this variant? 6)What treatments may be available for treatment of this patient? Include traditional types of treatments and any newer CFTR modulator treatments and how they work with this variant. The following web sites contain information about testing that can be done to identify the CFTR variants in humans.3https://www.acog.org/Patients/FAQs/Cystic-Fibrosis-Prenatal-Screening-and-Diagnosis#amhttps://ltd.aruplab.com/Tests/Pdf/182https://www.labcorp.com/test-menu/23686/cystic-fibrosis-cf-profile-32-mutations-fetal-analysisPossible TreatmentsThere are many old style standard therapies to treat CF, and there are the newer CFTR Modulator treatments. Which of these treatments might be useful for patients with your gene variant?As you do your database search, there will usually be some information thatcomes up about whether any of the newer modulator treatments is possible. There are other web sites where you can find specific information if you google the specific name of one of the new modulator treatments. Otherwise you should look into some of the older, standard treatmentsfor the disease. https://www.vertextreatments.com/https://www.cff.org/Life-With-CF/Treatments-and-Therapies/Medications/CFTR-Modulator-Therapies/https://investors.vrtx.com/news-releases/news-release-details/fda-approves-symdekor-tezacaftorivacaftor-and-ivacaftor-treatCystic Fibrosis Genetic Variants1.G542X2.W1282X3.R553X4.N1303K5.I507del6.G551D7.S549N8.R117H9.R347P10.D1152H11.A455E12.2789 + 5G -ASave the paper as a Word or PDF file to submit.There are two documents that are included in this project module. 1. The first document has information that will lead you to high quality web sites that will tell you more about cystic fibrosis and help you answer the questions that need to be covered in your paper. It will also walk you through the steps to get to the database that has the information about the mutation that you will be assigned. Look at all of the directions in that document along with the information found here in order to have a complete picture of the project.2. The second document has a table that will show you which mutation you have been assigned. The list of mutations is in the far left column; you will find your name in one of the rows to the right of one of the mutations. You may NOT switch you assignment with other students in the class. The specific mutation you are researching should be included in the title of your project.The completed project is worth up to 100 points and a grading rubric will be posted in the next couple of days. The completed project is due no later than July 30th at 11:59 PM.
13 pages
An Exploration Of The Diversity Of Life Lab
For this week’s lab we will divide the lab groups up by last name. Your kingdom/domain assignment will be listed after t ...
An Exploration Of The Diversity Of Life Lab
For this week’s lab we will divide the lab groups up by last name. Your kingdom/domain assignment will be listed after the first letter of your last ...
Earn money selling
your Study Documents