Need the following question answered for tetanus disease.

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1. Provide a brief history of this disease.

2. Identify cause (both genus/species names)

3. What is the epidemiology of this disease? (when, who, where, etc.)

4. What is the disease process in the human body? (i want an overview of the overall process, DO NOT provide a list of symptoms)

5. Are there any treatments (provide an overall view, NOT a list of medicine or dosages, etc.)

6. Are there any vaccines? (current or in the works)

Oct 2nd, 2015

Thank you for the opportunity to help you with your question!

One of the first written accounts of Tetanus was given by Hippocrates, BCE [1]. It is  caused by a bacteria Clostridium Tetani, which releases a toxin called Tetanospasmin. Tetanospasmin is among the deadliest toxins [3].  It affect humans, producing involuntary muscle spasm, and can result in death of the contaminated individual. There is a vaccine against it, which is listed as “List of Essential Medicine” by the World Health Organization (WHO) [2]. There are treatments for these disease for both the mild and severe cases. These may include the use of tetanus antibodies [1], and antibiotics for example.

Reference:

[1] Tetanus. In Wikipedia. Retrieved in October, 2015, from http://en.wikipedia.org/wiki/Tetanus

[2] Tetanus Vaccine. In Wikipedia. Retrieved in October, 2015, from http://en.wikipedia.org/wiki/Tetanus_vaccine.

[3] Tetanospasmin. In Wikipedia. Retrieved in October, 2015, from http://en.wikipedia.org/wiki/Tetanospasmin


Please let me know if you need help with any other questions.
Oct 2nd, 2015

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