c57 & berk experimental animal what are they?

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what are C57?

what are BERK?

what are BERK homo?

Oct 3rd, 2015

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C57/BL6 mice (genetic background strain of NY1DD and S+SAntilles)

C57BL/6, often referred to as "C57 black 6", "C57" or "black 6" (standard abbreviation:B6), is a common

inbred strainoflaboratory mouse.

It is the most widely used "genetic background" for genetically modified mice for use as models of human disease. They are the most widely used and best-selling mouse strain, due to the availability ofcongenicstrains, easy breeding, and robustness.[1]

C57BL/6 has many unusual characteristics that make it useful for some work and inappropriate for other: It is unusually sensitive to pain and to cold, andanalgesicmedications are less effective in it.[1][4]Unlike most mouse strains, it drinksalcoholic beveragesvoluntarily. It is more susceptible than average tomorphine addiction,atherosclerosis,[citation needed]and age-relatedhearing loss.[5]

In 2013 C57BL/6 mice were flown into space aboardBion-M No.1.[6]

In 2015 C57BL/6NTac females provided by Taconic Biosciences were sent to the International Space Station onSpaceX CRS-6.[7]

The inbred strain of C57BL mice was created in 1921 byC. C. Littleat theBussey Institute for Research in Applied Biology.[1]The substrain "6" was the most popular of the surviving substrains.


Hbss Berk are also laboratory mice used to study sickle cell pathology and pain



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Oct 4th, 2015

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