Thank you for the opportunity to help you with your question!
C57 are laboratory mice used in research
Berkeley sickle cell mice are used as an animal model for human sickle cell disease.
Refer to your other question for more detailed explanation on c57 '
In two mouse SCD models, Berkeley and SAD, inhibition of red blood cell dehydration and sickling was achieved with correction of hematological parameters,
splenomegaly, and prevention of the characteristic urine concentration