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Describe how a follicle matures.
At puberty, the anterior
pituitary gland secretes a greatly increased amount of FSH and the ovaries
enlarge in response. During this time, primary follicles are being formed from
some of the primordial follicles. As it matures, the oocyte of a primary
follicle grows larger, and the follicular cells surrounding it divide actively
by mitosis. The cells become organized into layers, and soon a cavity appears
in the cellular mass that becomes filled with a clear follicular fluid. This
fluid bathes the oocyte. This fluid-filled cavity continues to enlarge, and the
oocyte is pressed to one side. Over time, the follicle reaches a diameter of
ten millimeters or more and bulges outward on the surface of the ovary like a
blister. The oocyte within a mature follicle is a large, spherical cell,
surrounded by the zona pellucida and is enclosed by the corona radiata. As many
as twenty follicles may start this process but only one reaches full
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