Atherosclerosis, Write 800 to 850 words, health and medicine homework help

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Question Description

Atherosclerosis is a common disorder of the arteries. A modifiable risk factor for the development of atherosclerosis is hypertension. Discuss the pathophysiology of both disorders and the mechanisms by which hypertension contributes to atherosclerosis. Discuss the current medications used to treat both disorders and the pharmacologic actions the medications have in altering the pathophysiology. How can you use this information in your current or future practice setting?

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wambuiguama
School: Carnegie Mellon University

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Running head: ATHEROSCLEROSIS AND THE PATHOGENESIS OF HYPERTENSION

ATHEROSCLEROSIS AND THE PATHOGENESIS OF HYPERTENSION
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ATHEROSCLEROSIS AND THE PATHOGENESIS OF HYPERTENSION

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Atherosclerosis and the Pathogenesis of Hypertension
Hypertension, a well-known cardiovascular risk factor, increases the development of
atherosclerosis. Through studies and clinical trials, results have proven that, given reasonable
levels of quintile of diastolic pressure, coupled with the additional risk of smoking and higher than
normal levels of cholesterol, atherosclerosis develops purely from hypertension. From clinical
trials by Chobanian (2015), hypertension was induced into a Watanabe hyperlipidemic rabbit. The
outcome concluded the occurrence of a synergistic outcome leading to the intensification of
atherosclerosis in the rabbit. Observations on the abdominal aorta, the total surface of involvement
in the animals, there was a noticeable enhancement in the formation of a lesion that accompanied
the induced hypertension. There was a profound similarity between the low-density lipoprotein
receptor and the molecular defects in the hypercholesterolemic endogenous rabbits in the study.
The sim...

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