1.Discuss characteristic findings of immune dysfunction for either hypersensitivity reactions or AIDS. Explain what symptomology the patient would exhibit and how these symptoms may complicate daily living and relationships.2 - Discuss what symptoms are associated with anaphylactic shock and how the nurse differentiates these from other conditions or issues. What steps should be taken if the nurse suspects anaphylactic shock?

Assignment: Evidence-Based Project, Part 2: Advanced Levels of Clinical Inquiry and Systematic ReviewsYour quest to purchase a new car begins with an identification of the factors important to you. As you conduct a search of cars that rate high on those factors, you collect evidence and try to understand the extent of that evidence. A report that suggests a certain make and model of automobile has high mileage is encouraging. But who produced that report? How valid is it? How was the data collected, and what was the sample size?In this Assignment, you will delve deeper into clinical inquiry by closely examining your PICO(T) question. You also begin to analyze the evidence you have collected.To Prepare:Review the Resources and identify a clinical issue of interest that can form the basis of a clinical inquiry.Develop a PICO(T) question to address the clinical issue of interest you identified in Module 2 for the Assignment. This PICOT question will remain the same for the entire course.Use the key words from the PICO(T) question you developed and search at least four different databases in the Walden Library. Identify at least four relevant systematic reviews or other filtered high-level evidence, which includes meta-analyses, critically-appraised topics (evidence syntheses), critically-appraised individual articles (article synopses). The evidence will not necessarily address all the elements of your PICO(T) question, so select the most important concepts to search and find the best evidence available.Reflect on the process of creating a PICO(T) question and searching for peer-reviewed research.The Assignment (Evidence-Based Project)Part 2: Advanced Levels of Clinical Inquiry and Systematic ReviewsCreate a 6- to 7-slide PowerPoint presentation in which you do the following:Identify and briefly describe your chosen clinical issue of interest.Describe how you developed a PICO(T) question focused on your chosen clinical issue of interest.Identify the four research databases that you used to conduct your search for the peer-reviewed articles you selected.Provide APA citations of the four relevant peer-reviewed articles at the systematic-reviews level related to your research question. If there are no systematic review level articles or meta-analysis on your topic, then use the highest level of evidence peer reviewed article.Describe the levels of evidence in each of the four peer-reviewed articles you selected, including an explanation of the strengths of using systematic reviews for clinical research. Be specific and provide examples. Required Readings :USE AT LEAST 6 SOURSES 3 FROM THE FOLLOWINGMelnyk, B. M., & Fineout-Overholt, E. (2018). Evidence-based practice in nursing & healthcare: A guide to best practice (4th ed.). Philadelphia, PA: Wolters Kluwer.Chapter 2, “Asking Compelling Clinical Questions” (pp. 33–54)Chapter 3, “Finding Relevant Evidence to Answer Clinical Questions” (pp. 55–92)Davies, K. S. (2011). Formulating the evidence based practice question: A review of the frameworks for LIS professionals. Evidence Based Library and Information Practice, 6(2), 75–80.Library of Congress. (n.d.). Search/browse help - Boolean operators and nesting. Retrieved September 19, 2018, from https://catalog.loc.gov/vwebv/ui/en_US/htdocs/help...Stillwell, S. B., Fineout-Overholt, E., Melnyk, B. M., & Williamson, K. M. (2010). Evidence-based practice, step by step: Asking the clinical question: A key step in evidence-based practice. American Journal of Nursing, 110(3), 58–61.Melnyk, B. M., Fineout-Overholt, E., Stillwell, S. B., & Williamson, K. M. (2009). Evidence-based practice: Step by step: Igniting a spirit of inquiry. American Journal of Nursing, 109(11), 49–52. doi:10.1097/01.NAJ.0000363354.53883.58Stillwell, S.B., Fineout-Overhold, E., Melnyk, B.M., & Williamson, K.M. (2010). Evidence-based practice step-by-step: Searching for evidence. American Journal of Nursing, 110(5), 41-47.Walden University Library. (n.d.-a). Databases A-Z: Nursing. Retrieved September 6, 2019, from https://academicguides.waldenu.edu/az.php?s=19981Walden University Library. (n.d.-c). Evidence-based practice research: CINAHL search help. Retrieved September 6, 2019, from https://academicguides.waldenu.edu/library/healthe...Walden University Library. (n.d.-d). Evidence-based practice research: Joanna Briggs Institute search help. Retrieved September 6, 2019, from https://academicguides.waldenu.edu/library/healthe...Walden University Library. (n.d.-e). Evidence-based practice research: MEDLINE search help. Retrieved September 6, 2019, from https://academicguides.waldenu.edu/library/healthe...Walden University Library. (n.d.-f). Keyword searching: Finding articles on your topic: Boolean terms. Retrieved September 19, 2018, from http://academicguides.waldenu.edu/library/keyword/...Walden University Library. (n.d.-g). Keyword searching: Finding articles on your topic: Introduction to keyword searching. Retrieved September 19, 2018, from http://academicguides.waldenu.edu/library/keyword/... Walden University Library. (n.d.-h). Quick Answers: How do I find a systematic review article related to health, medicine, or nursing? Retrieved September 6, 2019, from https://academicanswers.waldenu.edu/faq/72670Walden University Library. (n.d.-i). Systematic review. Retrieved January 22, 2020, from https://academicguides.waldenu.edu/library/healthe...

Contact your local or state health department and identify a public health professional for a short interview assessing the utilization of core public health concepts in their work with the community population. This individual could be an epidemiologist, a WIC employee, a public health nurse, a sanitarian, etc. Questions to Ask: Describe the population/community in terms of their demographics (age, gender, ethnicity, etc.) and their current health status (mortality, illnesses, etc.).How do you gather this data? With what population do you specifically work in the community? Are they a vulnerable population and why? What services and programs are provided for this population? Which of the services are primary, secondary, or tertiary prevention? What health promotion and/or health education is provided for this population? What are the major challenges in your work in public health? What are the major satisfiers in your work in public health? What is needed to strengthen the public health system in our community? Be specific. Write at least two additional questions. Write the responses for each question directly underneath. Each response should be 2-3 paragraphs.