Description
1-describe the human microbiome from the perspective of human health and disease in no less than 500 words using at least 10 references.
2-design a diagnostic assay that can detect dysbiosis shwing the steps of design, samples used, analysis and outcome of the assay. describe how you can use this assay clinically.
Explanation & Answer
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Running Head: HUMAN MICROBIOME
Human Microbiome
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HUMAN MICROBIOME
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Question 1
Human microbiome
The human microbiome includes archaea, eukaryotes, bacteria, and viruses, which live
inside and outside the human body (Turnbaugh, Hamady, Fraser-Liggett, Knight and Gordon,
2007). These organisms affect human physiology, both health-wise and in diseases. This leads to
the contribution to the enhancement and diminishing of immune and metabolic tasks of the body.
These microorganisms take control of various parts of the human body. These microorganisms
adapt to various niches in the body.
More prevalent in the gastrointestinal tract are the facultative anaerobes (Huttenhower,
Gevers, Knight, Abubucker, Badger, Chinwalla, and Giglio, 2012). The strict anaerobes live in the
respiratory tract, skin exterior, and nasal cavity. Organisms native to the human body are well
adapted to the body's immune system since they interact with the body's immune system for a very
long time. A change of the intestinal microbiomes plays a crucial role in human health and ailment
pathogenesis (Methé, Nelson, Pop, Creasy, Giglio, Huttenhower and Chinwalla, 2012).
These changes ground themselves on the presence of underlying disease and routine.
Dysbiosis escalates the susceptibility of the host to be infected. Its nature also depends on the
structural spot involved. The exceptional variety of the animal's microbiota accounts for this
microorganism's precise metabolic tasks and purposes in each body site (Gilbert, Blaser, Caporaso,
Jansson, Lynch and Knight, 2018). The comprehension of the microbial composition and tasks of
the human microbiome is paramount since their contribution to health and disease is immense.
The interactions between humans and microbiomes may be pathogenic, commensality, and
mutualistic. These microbiomes are defined as the genomic contents of micro biodata living in a
certain part of the body (Caporaso, Lauber, Costello, Berg-Lyons, Gonzalez, A., Stombaugh and
HUMAN MICROBIOME
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Gordon, 2011). The organisms control the body, forming a diverse and distinct bio...
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