BIO 336 San Diego State University Actin Myosin Myofibrils Sarcolemma Exam Practice

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1 Principles of Human Physiology - Biology 336 Summer 2021 Schedule Number 77066 COURSE INFORMATION Class Days: ONLINE Class Times: ONLINE Class Location: Canvas and Zoom Mode of Delivery: ONLINE Lecture Instructor: Michael J. Buono, Ph.D. Phone: 619-594-6823 Email: mbuono@sdsu.edu EMAIL • If you need to email me, please include “BIO 336 Summer” in the subject line. This helps me keep the numerous emails I receive in order. Your email content should also include: your full (legal) name and your Red ID number. • In order to make myself available to all students, I will check my email at least once per day Monday-Thursday, at around 10:00am. I usually check my email more frequently; but you can be assured that I will check it at this time. During the weekday, I will try to respond to you within 24-hours, unless a course assessment is occurring. During the weekend, I will likely respond on Monday morning. Virtual Zoom Discussion section • The class is using a “reverse classroom” approach. You are required to watch the lecture material online, and then we will be holding discussion sections to clear up any questions you may have. I will be holding the virtual discussion sections using ZOOM on Mondays at 12 -1 pm and Tuesdays from 4-5 pm (PST). If you want to ask questions during that time, log onto ZOOM and the meeting ID is buono and the password is 336. The ZOOM discussion sessions will be recorded and posted to the class webpage so they will be available to review. If you want a ZOOM office meeting at a different time you would first need to contact me through email, so that we can set a time and day that work for both of us. Attendance at the ZOOM discussion sessions is NOT required. Zoom office hours and email will not occur May 31, as that is considered the summer session holiday in the SDSU academic calendar. COURSE MATERIALS 2 BOOK: The class will be using a FREE online book title “New Human Physiology” by E. Paulev. The www for the book is http://www.zuniv.net/physiology/book/ The material in the book should be considered reference material for clarification purposes only - as only the information covered in the 27 pre-recorded Mediasite lectures will be used to generate questions for the exams. MEDIASITE LECTURE RECORDINGS: You are responsible to watch 27 Mediasite video lectures that have been posted to the Canvas page. The Mediasite lecture recordings are copyright protected and strictly for you use in class. Do NOT copy them and post to social media sites or you will be prosecuted. They are previously recorded live lectures from my 2019 Spring semester Biology 336 class. During that semester the class was meeting face to face, so there was some discussion about bringing a red ParScore form to class for the exams. Naturally as we are doing the current class online, you do not have to use Parscore forms, so disregard that information. Exams during spring 2019 also had an essay question; however, your exams will be completely multiple-choice questions. You will be taking your 3 exams online from the class web page. Each lecture is approximately 75 min in length. You may watch them at your leisure as they should be available 24 hours a day. They can also be stopped and restarted in case you decide to not watch all 75 min of a lecture in one sitting. You can take notes and draw diagrams during the Mediasite lectures which you will be allowed to use during the exams. Please do not wait to watch the Mediasite lectures to the night before the exams. The SDSU Internet site and Canvas webpage have been known to experience connectively problems for several hours at a time. Thus, you may not have access to the Mediasite lectures during that time. Therefore a “word to the wise” is to stay current with your viewing of the prerecorded lectures. COURSE DESIGN COURSE DESCRIPTION: Physiology is the branch of biology that attempts to explain the phenomena displayed by living things (e.g. animals, plants). This course deals specifically with human physiology, with its main purpose to increase your knowledge and understanding of how the human body works. The course is organized to progress from the cellular level, to integrated system functioning (e.g., cardiovascular, pulmonary, etc.) to the total body. Numerous examples of related 3 pathophysiology and their pharmacological treatment are presented to allow you to compare and contrast “diseased” vs. normal physiological functioning, thus reinforcing conceptual understanding of the material. Your final grade in the class is based on the 3 exams, each of which counts as 32.3%, and on a written, thematic paper which counts for 3.1%. Extra credit assignments are not accepted in this class. Each test consists of 45-50 multiple-choice questions. You will take the exam online and will have approximately 1 min per question to complete the exam. The 3 exams can be found under the module tab of the class Canvas page. They are titled Parscore 1, 2 and 3, respectively. The topic for the written, thematic paper (500-1,000 words) is self-chosen and should involve the application of the physiological knowledge gained in BIO 336 to a pertinent current event. Specifically, in the 500 to 1,000 words you should summarize the chosen article and relate it to knowledge gained in class. Examples of the paper are available on the class Canvas page. The thematic paper is due by June 28th and should be uploaded to the class Canvas page. You do not have to upload the physiology related article you used to write the paper. Please do not email me your final paper. To receive credit, you must upload it to the Canvas web page. This is an Explorations course in Natural Sciences. Completing this course will help you learn to do the following with greater depth: 1) explain basic concepts and theories of the natural sciences; 2) use logic and scientific methods to analyze the natural world and solve problems; 3) argue from multiple perspectives about issues in natural science that have personal and global relevance; 4) use technology in laboratory and field situations to connect concepts and theories with real-world phenomena. GRADING POLICIES CLASS GRADES are assigned as follows: A = 90 - 100% 4 B = 80 - 89% C = 70 - 79% D = 60 - 69% F = 0 - 59% (+ and - grades will be assigned to the upper and lower 2% of each range, for example, 80 and 81% = B- while 88 and 89% = B+) SCHEDULE Topic (Chapters from New Human Physiology book) The class is broken down into three sections. During the first third of the class we will cover the following topics: Membrane Potential 1- 3 Action Potential – Conduction Synaptic Transmission/Lesion localization Neuromuscular Junction Skeletal Muscle Structure and Function During the second third of the class we will cover the following topics: Cardiovascular I: Structure & Function 8-12 Cardiovascular II: Electrophysiology Cardiovascular III: Hemodynamics/Cardiac cycle Body Fluid Regulation/Starling Forces/Edema 24 Respiratory I: Structure & Mechanics 13-16 5 Respiratory II: Gas diffusion Respiratory III: Hypoxia During the last third of the class we will cover the following topics: Renal Function and Diuretics 25 Blood Glucose Homeostasis 27 Diabetes Mellitus Reproductive endocrinology 29 • For the first third of the class you are responsible for the material covered in Mediasite video lectures titled Neuromuscular I through VIII which can be found in module I. The first exam is scheduled for June 3, 2021. Once the exam is accessed, the student must complete the exam within the allotted 60 min time (in one sitting). The Exam will auto-submit when the exam timer is up. The exam will become available at 8:00am (PST), and the exam will close at 8:00pm (PST). You may use written notes during the exam that you completed while watching the Mediasite lectures. • For the second third of the class you are responsible for the material covered in lectures titled Cardiorespiratory I through IX which can be found in module II. The second exam is scheduled for June 17, 2021. Once the exam is accessed, the student must complete the exam within the allotted 60 min time (in one sitting). The Exam will auto-submit when the exam timer is up. The exam will become available at 8:00am, and the exam will close at 8:00pm. You may use written notes during the exam that you completed while watching the Mediasite lectures. • For the last third of the class you are responsible for the material covered in lectures titled Renal and Endocrine I through X, which can be found in module 3. The third exam is scheduled for Thursday July 1, 2021. Once the exam is accessed, the student must complete the exam within the allotted 60 min time (in one sitting). The Exam will auto-submit when the exam timer is up. The exam will become available at 8:00am, and the exam will close at 8:00pm. You may use written notes during the exam that you completed while watching the Mediasite lectures. For a Crashed Exam and Troubleshooting: To reduce the risk of technical problems with your assessments, there are important rules to follow. All tests should 6 be taken on a computer-not a cell phone. Please make sure to use Chrome as your browser. If your test crashes, try to re-enter the assessment immediately. If you are unable to re-enter it, you should email me right away. If you have a problem accessing the pre-recorded lectures or the exams you can get help from the SDSU Library by calling 619-594-3189 or emailing hub@sdsu.edu Also Canvas can be contacted directly 24/7 from the page titled Canvas:Additional Support – on the class web page. Reviewing Exams: You will be allowed access to the graded exams via Canvas 2 days after you take the test. STUDENT LEARNING OUTCOMES FOR BIOL 336 1. Describe the structure of a neuron and explain the functional significance of its principle regions. 2. Explain the actions of voltage-regulated Na+ and K+ channels and describe the events that occur during the production of an action potential. 3. Discuss the role of the Na+/K+ pumps in the maintenance of the resting membrane potential. Explain the sliding filament theory of muscular contraction. Explain how tropomyosin and troponin control muscle contraction and 4. 5. 6. 7. 8. 9. 10. 11. relaxation, and describe the role of Ca2+ and the sarcoplasmic reticulum in excitation-contraction coupling. Describe the path of the blood through the heart and the function of the atrioventricular and semilunar valves. Describe the electrical activity in the sinoatrial node and explain why this tissue functions as the heart's normal pacemaker. List the factors that regulate the arterial blood pressure. Explain how the intrapulmonary and intrapleural pressures vary during ventilation and relate these pressure changes to Boyle's law. Describe the nature of asthma, bronchitis, emphysema, and pulmonary fibrosis. Describe the role of antidiuretic hormone (ADH) in regulating the final urine volume. 7 12. 13. 14. 15. Describe the different regions of the nephron tubules and the location of the tubules in the kidney. Discuss the physiological mechanism of commonly prescribed diuretics. Describe the actions of insulin and glucagon and explain how the secretion of these hormones is regulated. Describe the symptoms of type 1 and type 2 diabetes mellitus and explain how these conditions are produced. Discuss how oral hypoglycemic drugs work. Explain the temporal relationship between the 3 phases of the uterine cycle and the 3 phases of the ovarian cycle. Concepts BIOLOGY DEGREE LEARNING OUTCOMES LEVEL OF EMPHASIS Provide examples of the relation between form and function in biology, as expressed in molecular, cellular, and wholeorganism physiology Major component Compare and contrast the major cellular processes in eukaryotes and prokaryotes Not Addressed Explain how genetic information is transmitted, and the relationship between genetics and evolution Not Addressed Compare and contrast the primary mechanisms of evolutionary diversification Not Addressed Skills 8 Categorize the diversity of life in terms of the phylogenetic relationships among major organismal groups Not Addressed Describe how interactions among organisms and their environment influence populations, communities, and ecosystem function Not Addressed Quantitatively answer biological questions using mathematical or statistical tools Reinforced Design, conduct, and interpret experiments using common biological lab and field techniques Not Addressed Effectively and concisely present scientific ideas and the results of scientific research in written and oral form Reinforced Critique scientific papers, as demonstrated by written or oral summaries of hypotheses, methodology, and conclusions Reinforced UNIVERSITY POLICIES Student Responsibility for Catalog Information: Students are held individually responsible for the university policy information contained in the general catalog. The requirements listed in the Graduation Requirements section of the catalog are those requirements which the university will make every effort to preserve for students subject to this catalog. All other parts of the catalog, including the University Policies section, are subject to change from year to year as university rules, policies, and curricula change. Failure to keep informed of such changes will not exempt students from whatever penalties they may incur. Please refer to the university general catalog for any questions you may have that are not addressed in the course syllabus. Some information presented below is taken directly from the general catalog. Final Examinations: No final examination shall be given to individual students before the regular time. If you find it impossible to take a final examination on the date scheduled, you must make arrangements with the instructor to have an incomplete grade reported and must take the deferred final examination within the time allowed for making up incomplete grades. Expected time required for courses and outside study: You should expect to spend approximately 3 hours per week, in class and study time, for each unit of college work attempted. A normal 16-unit load, therefore, represents a 48-hour week. Note that the majority of this time estimate is spent outside of class. You should also keep in mind that some courses require more than the average amount of time, and that your 9 workload in all courses will vary throughout the semester as examinations and major papers or projects come due. Accommodations: If you are a student with a disability and are in need of accommodations for this class, please contact Student Ability Success Center at (619) 594-6473 as soon as possible. Please know accommodations are not retroactive, and I cannot provide accommodations based upon disability until I have received an accommodation letter from Student Ability Success Center. Student Privacy and Intellectual Property: The Family Educational Rights and Privacy Act (FERPA) mandates the protection of student information, including contact information, grades, and graded assignments. I will use Canvas to communicate with you, and I will not post grades or leave graded assignments in public places. Students will be notified at the time of an assignment if copies of student work will be retained beyond the end of the semester or used as examples for future students or the wider public. Students maintain intellectual property rights to work products they create as part of this course unless they are formally notified otherwise. Religious observances: According to the University Policy File, students should notify the instructors of affected courses of planned absences for religious observances by the end of the second week of classes. Academic Honesty: The University adheres to a strict policy prohibiting cheating and plagiarism. Examples of academic dishonesty include but are not limited to: • copying, in part or in whole, from another's test or other examination; • obtaining copies of a test, an examination, or other course material without the permission of the instructor; • collaborating with another or others in work to be presented without the permission of the instructor; • falsifying records, laboratory work, or other course data; • submitting work previously presented in another course, if contrary to the rules of the course; • altering or interfering with grading procedures; • assisting another student in any of the above; • using sources verbatim or paraphrasing without giving proper attribution (this can include phrases, sentences, paragraphs and/or pages of work); • copying and pasting work from an online or offline source directly and calling it your own; • using information you find from an online or offline source without giving the author credit; • replacing words or phrases from another source and inserting your own words or phrases. • You may not text, email or call anyone during the exam, including using group text platforms such as GroupMe. The California State University system requires instructors to report all instances of academic misconduct to the Center for Student Rights and Responsibilities. Academic dishonesty will result in disciplinary review by the University and may lead to probation, 10 suspension, or expulsion. Instructors may also, at their discretion, penalize student grades on any assignment or assessment discovered to have been produced in an academically dishonest manner. Cheating and Plagiarism: In preparing and submitting materials for academic courses and in taking examinations, a student shall not yield to cheating or plagiarism, which not only violate academic standards but also make the offender liable to penalties explicit in Section 41301 of Title 5, California Code of Regulations as follows: Expulsion, Suspension, and Probation of Students. Following procedures consonant with due process established pursuant to Section 41304, any student of a campus may be expelled, suspended, placed on probation, or given a lesser sanction for one or more of the following causes that must be campus related. Cheating is defined as the act of obtaining, or attempting to obtain, credit for academic work by the use of dishonest, deceptive, or fraudulent means. Examples of cheating include, but are not limited to: • • • • • • • • • • copying, in part or in whole, from another’s test or other examination; discussing answers or ideas relating to the answers on a test or other examination without the permission of the instructor; obtaining copies of a test, an examination, or other course material without the permission of the instructor; using notes, cheat sheets, or other devices considered inappropriate under the prescribed testing condition; collaborating with another or others in work to be presented without the permission of the instructor; falsifying records, laboratory work, or other course data; submitting work previously presented in another course, if contrary to the rules of the course; altering or interfering with the grading procedures; plagiarizing, as defined; and knowingly and intentionally assisting another student in any of the above. Plagiarism is defined as the act of incorporating ideas, words, or specific substance of another, whether purchased, borrowed, or otherwise obtained, and submitting same to the university as one’s own work to fulfill academic requirements without giving credit to the appropriate source. Plagiarism shall include but not be limited to: • • • submitting work, either in part or in whole, completed by another; omitting citations for ideas, statements, facts, or conclusions that belong to another; omitting quotation marks when quoting directly from another, whether it be a paragraph, sentence, or part thereof; 11 • • • close and lengthy paraphrasing of the writings of another; submitting another person’s artistic works, such as drawings, musical compositions, paintings, photographs, or sculptures; and submitting as one’s own work papers purchased from research companies. Medical-related absences: Students are instructed to contact their professor/instructor/coach in the event they need to miss class, etc. due to an illness, injury or emergency. All decisions about the impact of an absence, as well as any arrangements for making up work, rest with the instructors. Student Health Services (SHS) does not provide medical excuses for short-term absences due to illness or injury. When a medical-related absence persists beyond five days, SHS will work with students to provide appropriate documentation. When a student is hospitalized or has a serious, ongoing illness or injury, SHS will, at the student's request and with the student’s consent, communicate with the student’s instructors via the Vice President for Student Affairs and may communicate with the student’s Assistant Dean and/or the Student Ability Success Center. Resources for students: A complete list of all academic support services--including the Writing Center and Math Learning Center--is available on the Student Affairs’ Academic Success website. Counseling and Psychological Services (619-594-5220) offers confidential counseling services by licensed therapists; you can Live Chat with a counselor at http://go.sdsu.edu/student_affairs/cps/therapist-consultation.aspx between 4:00pm and 10:00pm, or call San Diego Access and Crisis 24-hour Hotline at (888) 7247240. SDSU Economic Crisis Response Team: If you or a friend are experiencing food or housing insecurity, or any unforeseen financial crisis, visit sdsu.edu/ecrt, email ecrt@sdsu.edu, or walk-in to Well-being & Health Promotion on the 3rd floor of Calpulli Center.
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