West Coast University Pernicious Anemia Case analysis

User Generated

Genl12

Science

West Coast University

Description

Teri goes to see her PCP after feeling depressed last couple of months as well as experiencing a seizure earlier this week. The physician orders a few test, results are shown below:

  • Low hematocrit
  • Low levels of Vit B12
  • Low Oxygen levels
  • Presence of autoantibodies against the parietal cell
  • Peripheral blood smear shows abnormal RBC (large pale RBCs)

After viewing the results, Teri is diagnosed with Pernicious Anemia; a condition in which autoantibodies destroys the parietal cells found within the stomach.

Address each of the following regarding Teri’s case:

  1. Since the parietal cell is destroyed, which substance(s) is Teri lacking as a consequence?
  2. What is the correlation between destruction of parietal cells and Vit B12 deficiency?
  3. Due to her condition, Teri lacks Pepsin. Explain why.
  4. If Teri were healthy, explain what her RBCs would look like?
  5. What is hematocrit?
  6. Low oxygen levels stimulate her body to create new RBCs by stimulating which process? Explain that process in depth.
  7. What protein transports oxygen in our body and explain its structure?
  8. What cell secretes antibodies and explain the various functions of antibodies.
  9. What are the different types of antibodies and give two characteristics for each?
  10. Explain the structure of an immunoglobulin.

Specifics:

  • Support your opinions with evidence from your readings and research.
  • You must reference a minimum of three (3) scholarly sources in your paper, which includes one non-Internet source.
  • Use current APA Style to format your paper and to cite your sources.
  • Your paper/total responses must be 3– to 4-pages in length not including the title page, abstract, and reference pages.
    • Title page: Case Title, Full Name, Section, Date, Instructor and Campus
    • Abstract: Summarize the case in a paragraph
    • Introduction: The physiological importance of the digestive system, immune system, and cardiovascular system for the proper functioning of the human body
    • Body: Organize your analysis with headings that thoroughly answer the prompts
    • Conclusion: Summarize the paper in a paragrap

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Explanation & Answer

View attached explanation and answer. Let me know if you have any questions.

1

Case Analysis: Pernicious Anemia

Author
Affiliation
Instructor
Course
Date

2

Abstract
Pernicious anemia is a condition that arises from the impairment of the parietal cells in the
stomach walls. The impairment leads to the insufficiency of the intrinsic factor (IF), which
facilitates the synthesis of vitamin B12, facilitating the action of hemoglobin in the red blood
cells (RBCs). People suffering from the condition have low hematocrit thus low oxygen levels in
the blood. Pernicious anemia is preventable through proper nutrition and avoidance of unhealthy
practices like alcohol and substance consumption.

3

Introduction
The digestive system is essential to the human body since it is the primary way to get
nutrition. It comprises the alimentary canal and the capillaries attached to the ileum and colon.
The system breaks down food into nutrients necessary for cell growth, development and repair,
and energy supply required for metabolism. The digestive system digests the food and fluid into
molecules that are easily absorbable into the bloodstream. The system is also a way to eliminate
unwanted food material through secretion. Moreover, the digestive system facilitates the
prevention of certain diseases through the synthesis of critical hormones. For instance, the
parietal cells of the stomach walls synthesize the intrinsic factor, which increases the production
of vitamin B12, preventing pernicious and other forms of anemia.
The immune system is the foundational protection for the human body. The system
facilitates survival...


Anonymous
This is great! Exactly what I wanted.

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