- Record the Label strength of a tablet
according to the bottle information. 675mg CaCO3 and 135mg MG(OH)2
- Individually weigh 3 tablets and
determine the average tablet weight. Average weight 2.5755g
3. A number of tablets have been pre-ground to
provide the class with sufficient tablet powder for this experiment.
A. Assay for
1. Transfer an accurately weighed portion of the
powder, equivalent to about 1000 mg of calcium carbonate, to a beaker with the
aid of 60 mL of water, and add 100 mL of 1 N hydrochloric acid.
on a hotplate for 30 minutes in the hood, allow to cool, transfer with the
aid of water to a 250-mL volumetric flask, dilute with water to volume, mix,
and filter through filter paper on a glass funnel.
- Transfer 20.00mL of the filtrate to a
suitable container, dilute with water to 100 mL,
30 mL of 1 N sodium hydroxide, 5 mL of triethanolamine, and 100 mg of hydroxy
- Titrate with 0.05 M edetate disodium VS
until the solution is blue in color.
Repeat for a total of 3 times.
For the Report
mL of 0.05 M edetate disodium is equivalent to 5.004 mg of calcium carbonate
My volume is 19.96
the amount of Calcium Carbonate (CaCO3, 100.086 g/mol)
in the 20.00mL portion (step 6),
in the portion of the tablet powder weighed
and in an individual tablet - Report in mg/tab
and % of label strength.
The report is what i need to calculation