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Immunology , health and medical assignment help

Question Description

Prepare a 10 page document on tumor immunology. Use medical terms

Final Answer

Attached.

Leukocyte Activation and Migration (chapter 13)
Jonathan S. Reichner, PhD
Inflammatory Response
occurs immediately after wound
first stops bleeding
basically: white blood cells leaving bloodstream and attacking site of injury/infection
neutrophils leave blood stream first
makes sense: you want a phagocyte there
selection/pathway that gets right cell to right place at the right time
T cells don't go to local injuries
T cells are always circulating from the lymph nodes around the circulation
inflammation is due to more cells in one place than normal, and more fluid from vessels leaking out with
cells
memory B cells: recirculate like T cells, but preferentially circulate to where the infection that they are
specific for originated
1. blood clot (fibrins, platelets, etc)
2. granulocytes respond (professional phagocytes, chemicals are already packaged in granules; not much gene
expression change because they are designed to react quickly)
- neutrophil: first responders, keep wound area as sterile as possible; very similar to T cells recirculating
(threelobed nucleus)
- basophil: allergies (small and granular)
- eosinophil: allergies (small and granular)
- monocyte: becomes macrophage, later stage

- how do neutrophils know w...

RueJ (201)
UIUC

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