CMU Human Genome Project Discussion

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https://video.search.yahoo.com/search/video?fr=uh_magentertain_web_gs&p=cracking +the+code+of+life+video#id=1&vid=da593c1f44aa53bdb922ada850e52e09&action=vie w From the Film 1. What was the purpose of the Human Genome Project? 2. What is Tay-Sachs disease? How is it inherited? 3. Gene Therapy – What is Gene Therapy? From the film and these two sites – What are the dangers and promises of gene therapy (why does it sometimes work but not always?) https://medlineplus.gov/genesandgenetherapy.html Another thing that people are trying is called Gene Editing - what is it and how is it likely to change what it means to be human? http://genetics.thetech.org/editing-our-dna-molecular-scissors (Links to an external site.)Links to an external site. (Links to an external site.)Links to an external site. https://singularityhub.com/2017/04/18/gene-editing-could-change-what-being-human-actuallymeans/ (Links to an external site.)Links to an external site. (Links to an external site.)Links to an external site. 4. From the film - A) What was the Iceland Genetic Database project about? What is the purpose of the project and how did the researchers plan to carry it out? Note that DeCode was acquired by Amgen, a California Company, for $415 million dollars in 2012 and there is an ongoing debate about what they are going to do with the Icelandic database. 4. B) Genetic tests are becoming more common as scientists link genes to more diseases. There are currently over 2,000 genetic tests. This site run by the National Library of Medicine and other organizations is a good reference to understanding diseases with genetic components. Go to this site and pick a disease https://medlineplus.gov/genetics/condition/ What disease did you pick? What are the symptoms of this disease? How is it inherited? Do you think genetic testing will help to cure or prevent this disease? Why or why not? 5A. From the film - why is it dangerous to have mutations in the BRCA1 or BRCA2 genes? 5B. It is now getting to the point where genes could be removed from egg or sperm cells prior to fertilization (if in vitro fertilization is used). Do you support the idea of genetically designing babies? Do you think this could lead to a new eugenics movement? See link www.wiringthebrain.com/2013/05/the-new-eugenics-same-as-old-eugenics.html (Links to an external site.) (Links to an external site.) (Links to an external site.)Links to an external site. (Links to an external site.)Links to an external site. 6A. After viewing the Human Genome film, what do you think are the most positive (or best) aspects of the Human Genome Project (and how the results could be used in the future to change our lives)? 6B. After viewing the Human Genome film, what do you think are the worst (or most dangerous) aspects of the Human Genome Project?
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Human Genome Project

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Genome Project
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What was the purpose of the Human Genome Project?
What is Tay-Sachs disease? How is it inherited?
Gene Therapy – What is Gene Therapy?
a. What was the Iceland Genetic Database project about? What is the project's purpose,
and how did the researchers plan to carry it out?
b. The disease I picked? What are the symptoms of this disease? How is it inherited? Do
you think genetic testing will help to cure or prevent this disease? Why or why not?
5. Why is it dangerous to have mutations in the BRCA1 or BRCA2 genes?
6. Do you support the idea of genetically designing babies? Do you think this could lead to
a new eugenics movement?
7. a. The most positive (or best) aspects of the Human Genome Project
b. The worst (or most dangerous) aspects of the Human Genome Project?

According to the cracking of the code of life video, the purpose of the human genome
project is to study the full set of human genes and portray them for further biological study. The
human genome project also helps determine the full sequence of DNA in the humanoid genome
(NOVA, 2022). Also, the cracking of the code of life video defines the Tay Sachs disease is a
rare genetic disorder inherited from parents to children. It is mostly caused by the lack of
enzymes that break down fatty materials. It is inherited as a result of a mutation in the HEXA
gene from the child's biological parents. From the singularity website, gene therapy has many
risks since it can't be inserted directly into one’s cells. Otherwise, they may cause unwanted
system reactions to target the wrong cells, which may cause tumors (2022). On the other side,
gene therapy's major advantage is that it promises a continuing expression of genes that allow for
treatment following one treatment rather than continuously taking of drug with a very short halflife. Sometimes, gene therapy may help recover the original capability of a cell DNA hence
helping cure the mutation. In some cases, gene therapy...


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