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School: UIUC





Dissertation Prospectus

Dissertation Prospectus
Topic: The Prevalence and Awareness of Sickle Cell Disease a Case Study of African and
African-Americans Communities
Problem Statement
Worth a note, sickle-cell disease is a group of genetically acquired disorder that makes
the affected individual to possess abnormal hemoglobin in their erythrocytes. Notably, the signs
and symptoms of sickle-cell disease include pain crises, leg ulcers, fatigue, anemia, dactylitis and
arthritis, lung and heart injury, as well as splenic sequestration and liver congestion. Important to
note, for an offspring to inherit sickle-cell anemia, both parents must possess either sickle-cell
anemia or one sickle cell gene or trait. In addition, being African American, Hispanic, Middle
Eastern, Asian, Indian or of Mediterranean descent is a risk factor to sickle-cell disorder is a
prevalent condition among African/African-Americans affecting about 70,000 to 100,000
Americans (CDC,2016). Besides, the condition is attributed to genetics, race, and health; thus,
becoming a warranting issue that requires addressing. More so, it is estimated that 1 in every 365
live births of black or African-American is affected by sickle-cell disease, 1 out of every 16,300
Hispanic-American births has sickle-cell disease, and 1 in 13 Black or African-American possess
the sickle-cell trait. Moreover, most of the African Americans and blacks carry the sickle cell
trait without their knowledge resulting to a genetic transition of sickle cell diseases upon
marrying an SCT carrier without knowing Harrison (2011).. Further, although some individuals
may be aware of the condition existence, most lack insight concerning the symptoms,
complications, and treatment options. Besides, , Derebail et al., (2010) postulate that it has been
affecting individuals of African descent for centuries. Further, the condition impacts adults as



well as children; hence, making it indispensable for people to understand SCD to aid in the
implementation of programs that would assist both adults and kids in overcoming hurdles related
to SCD.
The purpose of this research is to investigate the prevalence of sickle cell disease among
African/ African-Americans, Therefore, to address the gap, the approach used will be based
primarily on quantitative and qualitative method. Thus, the study will seek to extend the findings
generated from the problem statement with the primarily aim at creating awareness regarding the
prevalence of sickle cell disease and trait among Africans and Black Americans to both the
general population and the public sectors....

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