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Review the hypothalamus, pituitary, and ovarian axis, and explain the pathophysiology of
PCOS. Explain the role of hormones in the development of this disorder. How does PCOS
contribute to infertility?
The hypothalamus, pituitary, and ovarian axis is combination of endocrine glands that
treats them like a single entity. These glands are viewed as a single system because they function
together in endocrinologists and physiologist. This axis has a primary role in the development as
well as regulation of different body systems which include the immune and reproductive
systems. Variations in this axis often results in the different gland glands to produce different
hormones. These hormonal secretionshave different effects to the body (Romeo, 232-240).
Polycystic Ovary Syndrome (PCOS) is one of the disorders occasioned by an irregular
fluctuation in this axis. POS is a disorder caused by an imbalance of these hormones and it
affects females in the reproductive age. The affected individuals may experience irregular or
extended menstrual periods, high levels of androgen hormones, or the formation of follicles in
the ovaries causing irregular ovulation. Besides irregular ovulation, the sufferers may ovulate
immature eggs or fail to ovulate at all thus reducing the chances of getting pregnant thus leading
Mr. Jones, a 60-year-old male, was seen for his yearly physical. Upon review of his lab
results, a high PSA level was seen. Having heard about th...