HHS Public Access Author manuscript Author Manuscript J Orthop Sports Phys Ther. Author manuscript; available in PMC 2021 March 05. Published in final edited form as: J Orthop Sports Phys Ther. 2019 December ; 49(12): 917–924. doi:10.2519/jospt.2019.8945. Abnormal Joint Loading During Gait in Persons With Hip Osteoarthritis Is Associated With Symptoms and Cartilage Lesions Author Manuscript TZU-CHIEH LIAO, PT, PhD1, MICHAEL A. SAMAAN, PhD2, TIJANA POPOVIC1, JAN NEUMANN, MD3, ALAN L. ZHANG, MD4, THOMAS M. LINK, PhD1, SHARMILA MAJUMDAR, PhD1, RICHARD B. SOUZA, PT, PhD1,5 1Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA. 2Department 3Technical of Kinesiology and Health Promotion, University of Kentucky, Lexington, KY. University Munich, Munich, Germany. 4Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA. 5Department of Physical Therapy and Rehabilitation Science, University of California San Francisco, San Francisco, CA. Abstract Author Manuscript BACKGROUND: Hip joint loading in persons with hip osteoarthritis (OA) is not well studied, and its associations with symptoms and lesions are unknown. OBJECTIVES: To determine whether hip joint loading differs between people with and without radiographic hip OA, and to identify its associations with patients’ symptoms and cartilage morphology. Author Manuscript METHODS: Forty-eight patients (28 male; mean ± SD age, 56.0 ± 12.2 years) with hip OA and 95 controls (40 male; age, 43.2 ± 13.6 years) participated in this cross-sectional analysis. Pelvic radiographs, questionnaires, magnetic resonance imaging (MRI), and gait analysis were conducted. The Hip disability and Osteoarthritis Outcome Score (HOOS) was used to assess symptoms. Cartilage morphology was graded on MRI scans using the Scoring Hip Osteoarthritis with Magnetic Resonance Imaging (SHOMRI) system. Biomechanical variables included peak external hip joint moment (Newton meters per kilogram) and moment impulses (Newton meters times milliseconds per kilogram) in all planes. Generalized estimating equations were used to compare the biomechanical characteristics between groups. In the patients with OA, associations of moment impulses with HOOS and SHOMRI scores were assessed with partial correlations. RESULTS: The OA group exhibited higher peak external hip flexion and adduction moments (P
Purchase answer to see full attachment