Question Description
I'm working on a health & medical multi-part question and need an explanation and answer to help me learn.
Please read the following section in the ACR Manual:
MRI Contrast Agents and Adverse Reactions
Pre-medication for GBCA
- MRI Contrast Agents and Pregnancy
- MRI Contrast Agents and Breast feeding mothers
- MRI Contrast Agents and Nephrogenic Systemic Fibrosis (NSF)
- 2. CREATE a GBCA guide (notebook) for yourself from the information in this manual.in these sections
- 3. Write a script of how you will communicate information regarding contrast safety to your patients who are receiving contrast and for those who are pregnant or breast feeding
Explanation & Answer
View attached explanation and answer. Let me know if you have any questions.
Running head: ACR CONTRAST MANUAL
ACR Contrast Manual
Student Name
University Name
1
ACR CONTRAST MANUAL
2
ACR Contrast Manual
Contrast agents are commonly used in magnetic resonance imaging (MRI) screening to
help in differentiating between abnormal and normal tissues by changing their relaxation times.
In particular, the commonly used contrast agent in clinical MRI screening is the Gadoliniumbased contrast media/agent (GBCA), which is because it is considered to be well tolerated by
most of the patients that it has been used on since its approval for parenteral use in the late
1980s. Moreover, GBCA is preferred for most individuals receiving MRI screening based on its
stability, chelate chemistry, osmolality, viscosity, as well as its effectiveness for specific clinical
usage. Nevertheless, GBCA use in MRI screening has been found out to lead to adverse
reactions being experienced by specific patients, including patients with asthma or allergies,
patients with a previous reaction to GBCA as well as previous reaction to iodinated contrast
agents, patients with pregnancy, and patients who are breastfeeding. In this light, the purpose of
this guide is to inform patients on contrast safety precautions to consider for GBCA
administration, including the adverse reactions, and its administration to patients who are
pregnant or breastfeeding as directed in the ACR manual on contrast media by ACR Committee
on Drugs and Contrast Media (2021).
Adverse Reactions
In general, the event rate for adverse reactions associated with GBCA use at the standard
clinical dose ranges between 0.07 and 2.4 percent. Essentially, most reactions are physiologic
and mild, including headache, warmth, coldness, nausea (with or without vomiting), dizziness,
paresthesias, and pain at the site of injection. Furthermore, allergic-like reactions asso...