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School: UIUC



Dissertation Prospectus
Student’s Name
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Dissertation Prospectus

Topic: The Prevalence and Awareness of Sickle Cell Disease a Case Study of African and
African-Americans Communities
Problem Statement
Worth a note, sickle-cell disease is a group of genetically acquired disorder that makes the
affected individual possesses abnormal hemoglobin in their erythrocytes. Notably, the signs and
symptoms of sickle-cell disease include pain crises, leg ulcers, fatigue, anemia, dactylitis and
arthritis, lung and heart injury, as well as splenic sequestration and liver congestion. Important to
note, for an offspring to inherit sickle-cell anemia, both parents must possess either sickle-cell
anemia or one sickle cell gene or trait. In addition, being African American, Hispanic, Middle
Eastern, Asian, Indian or of Mediterranean descent is a risk factor for sickle-cell disorder is a
prevalent condition among African/African-Americans affecting about 70,000 to 100,000
Americans. Besides, the condition is attributed to genetics, race, and health; thus, becoming a
warranting issue that requires addressing. More so, it is estimated that 1 in every 365 live births
of black or African-American is affected by sickle-cell disease, 1 out of every 16,300 HispanicAmerican births has sickle-cell disease, and 1 in 13 Black or African-American possess the
sickle-cell trait. Most of the African and African Americans carry the sickle cell trait without
their knowledge resulting to a genetic transition of sickle cell diseases upon marrying an SCT
carrier Harrison (2011). There is limited awareness of sickle cell disease among the African and
African-American communities (Boyd, Watkins, Price, Fleming, and DeBaun, 2005). More so,
although some individuals may be aware of the existence of the condition, most lack insight
concerning the symptoms, complications, and treatment options. Besides, Derebail et al., (2010)
postulate that it has been affecting individuals of African descent for centuries. Notably, the



condition affects persons at all ages; and hence, making it necessary for people to understand
SCD and aid in the implementation of programs that would assist affected persons in overcoming
hurdles related to SCD.
The purpose of this research is to investigate the prevalence of sickle cell disease among
African and African-Americans. Therefore, to address the gap, the approach used is based
primarily on quantitative and qualitative methods. The study will seek to extend the findings
generated from the problem statement, with the primary aim of creating awareness regarding the
prevalence of sickle cell disease and trait among African and African-Americans, to both the
general population and the public sectors. As a result, the evaluation of the problem statement
will be utilized together with the results from the data analysis to provide recommendations and
strategies regarding the control of sickle cell disease and other SCD related health issues.
The significance of the study is to address the prevalent issue sickle cell disease among
the Blacks and African-Americans communities. There lacks enough research to educate persons
on the influence of genetic, health, and race, which has led to the increased rate of SCD as well
as its related health problems among the United States population. Moreover, the research aims
at creating awareness to the public concerning the risk factors of SCD, which are race, and
genetics; thus, resulting to unfavorable environmental and societal conditions that have become a...

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