Developmental biology

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Jnynn

Science

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There is a 5 pages article you need to read and then answer 4 questions related to this article.

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Attached.

Running Head: BIOLOGY DEVELOPMENT

Biology Development
Institutional Affiliation
Date

1

BIOLOGY DEVELOPMENT

BIOL 316

2

Name_________________

Take Home Quiz 1 36pts total
Dupressoir et al., 2009
Read questions carefully: many require more than one answer!
Do not copy and paste answers from the paper- write in your own words!
Complete homework as a Microsoft Word document and submit via Turn It In on
Ecampus

1.

Function and origin of syncytins (8 pts):

a.

Where did the syncytin genes come from?

It is actually been revealed that syncytin genes in most of the cases they are typically
formed like a forerunner to the cellular layer formation which permits for placenta as well
as uterus fusion. Syncytin genes initially started like a viral gene deliberated purposely
generate proteins which are more likely to fuse the host’s cell jointly, thus permitting the
virus to stretch with greater ease (Georgiades, Ferguson-Smith, Burton 2002)
b.

How did they end up in the mammalian genome?

In mammalian genome, trophoblast cell as well as tissues which are from-embryo
syncytium created from the material as well as fetal cells nutrients typically pass them
from the material to the embryonic blood from end to end of these cells.
c.

What do cells in vitro (in a culture dish), do when expressing syncytins?

The main syncytins expression sites are typically placental syncytiotrophoblasts. The
recombinant syncytin expression within a broad cell type’s diversity induces giant
syncytia creation as well as that human trophoblastic fusion of cell line. The cell in most

BIOLOGY DEVELOPMENT

of the cases they indicate that syncytin is more likely to mediate fusion of placental
cytotrophoblast in vivo.
d.

What was the ancestral (original) function of s...


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