Houston Baptist University The Transforming Principle Discussion

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Houston Baptist University

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I'm working on a genetics multi-part question and need an explanation and answer to help me learn.

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1. One genome is comprised of 35% adenine. Another genome is comprised of 25% adenine. A third genome is comprised of 10% adenine. a. Determine the percentages of the remaining three DNA bases for each genome. 2. Avery, MacLeod, and McCarty demonstrate that DNA was responsible for the hereditary material and not protein or RNA. Using the following terms, describe their experiment that demonstrated this. Figures may be used to illustrate the experiment. Terms: transformation, smooth bacteria, rough bacteria, DNase, Protease, RNase 3. Describe how the histone functions as an octomer? a. What are each of the different subunits composed of? b. What is the function of histone H1?
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Proteases, enzymes that break down proteins, did not eliminate the transforming principle, according to
Avery and McCarty. Neither did the lipid-digesting enzymes known as lipases. They discovered that the
transforming substance had a lot of nucleic acids, but ribonuclease, which breaks down RNA, did not
render it inactive. Oswald Avery's team demonstrated that DNA was the "transforming principle" in a
remarkably straightforward experiment. DNA was able to change another strain of bacteria when it was
isolated from one strain and impart traits to the other strain. Hereditary information was carried by DNA.

Oswald Avery, Colin MacLeod, and Maclyn McCarty conducted the Avery-MacLeod-McCarty experiment,
which they reported on i...

oreavxn (1758)
UC Berkeley

Really useful study material!


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