Case 4 DHS 652 Identify the research design used by Larsson et al

User Generated

Xvyengu

Health Medical

DHS652

Trident University International

Description

Research Design

  1. Identify the research design used by Larsson et al (2005). Evaluate whether this research design is appropriate for this study. Include discussion of strengths and weaknesses as it relates to this specific study.

Sampling Method

  1. Describe the sampling method used by Larsson et al (2005). Evaluate the strengths and weaknesses of the sampling method as it relates to this specific study.

Sample Size

  1. In the study conducted by Larsson et al (2005), did the researchers have sufficient statistical power to detect an association between autism risk and preeclampsia? Provide support for your answer by including alpha and effect sizes (i.e. phi and measure of association). Also reference the statistical calculator used.
  2. How much statistical power did the researchers have to detect a statistically significant association between the risk of autism and low Apgar score at five minutes? Provide support for your answer by including the alpha and effect sizes. Also reference the statistical calculator used.
  3. If a researcher received a large grant to conduct further studies on the association between psychiatric history and autism risk (to address the issues posed in the Discussion section), what recommendations would you make regarding study design, sampling method, and sample size? Why?

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Explanation & Answer

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Research Study Analysis
Larsson et al (2005) conducted a research to determine the causal relationship between social
economic status, parental psychiatric history, and perinatal factors, and the risk of autism. By
collecting data from national registries, children born after 1972 in Denmark and at the risk of
being diagnosed with autism were monitored and studied until the year 1999. Cases of children
diagnosed with autism totalled 698; each case was matched to 25 controls by gender, birth year,
and age. With reference to this specific study, this paper will analyze the research design used,
evaluate the appropriateness of this research design as well as determine its strengths and
weaknesses. It shall also investigate the sampling method used in the study in terms of its
strengths and weakness. Apart from that, this paper will analyze the sample size and determine
the statistical power for associating autism risk and preeclampsia. Finally, it shall provide
recommendations regarding the most appropriate study desi...


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