Artificial selection has produced advantages that are profound on the global scale. One such sector of analysis is agriculture (http://evolution.berkeley.edu/evolibrary/article/evo_30). The overwhelming application of genetic mutation employed by agribusiness has enabled nations to address food security issues. However, the disadvantage conferred by this particular application of artificial selection is overpopulation. It is not clear whether agribusiness will be sustainable in the long term.
Socially, artificial selection has also produced growing concerns about the production of children genetically engineered for specific traits. Although much of the concern is unwarranted, there is danger wherever artificial selection disturbs populations-- such as in countries where male children are preferred over females.
Artificial selection has distinct disadvantages seen in the overuse of antibiotics. Bacterial antibiotic resistance is a very important issue to address, but not one that has an easy answer. Artificial selection is an unintended consequence of the overuse of antibiotics and has led to strains of harmful pathogens such as MRSA (http://www.mayoclinic.org/diseases-conditions/mrsa/basics/definition/con-20024479).
The use of such information in society has become more readily available, and its proliferation has led to people being tested for diseases long before there could be symptoms. A common test these days is analysis for the BRCA mutation linked to breast cancer (http://www.mayoclinic.org/tests-procedures/brca-gene-test/basics/definition/prc-20020361). Doubtless this information will allow women to make healthcare choices that are good for them. Such information does carry with it the risk of making healthcare choices on either 1) Faulty data, or 2) Statistically unlikely data. There is no absolute guarantee one way or the other that a person will develop an ailment.
To the extent that we as a society have had our culture catch up to artificial selection, the proliferation of genetic information has allowed beneficial choices and planning.
I don't know if you know this, but the "easy" questions only give us 20 minutes to answer-- there's a countdown clock. So it's almost impossible to get good sources and actually use them.
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