Running Head: ASSIGNMENT PAPER
1. The module mentioned that sickle cell disease was an adaptive response against
malaria. Why do you think such an adaptation occurred? Why do people who no
longer live in parts of the world where malaria is prevalent still develop the disease?
A recent research study showed that individuals with the gene for sickle-cell disease are
safe from malaria. In fact, this study can be used to find a cure for malaria. Sickle-cell is a
disease that occurs when the red blood cells are peculiarly shaped. Individuals with this
condition often inherit two abnormal copies of the gene for the oxygen-carrying protein
hemoglobin. The abnormal gene continues even carrying one copy of the gene carries some
resistance to malaria.
According to the findings made by scientists in the Gulbenkian Institute of Science in
Oeiras, Portugal, sickle-cell gene does not safeguard one from malaria infections but prevents
malaria from taking hold of the infected individuals. Therefore, sickle-cell disease is an adaptive
response against malaria because people with the sickle-cell condition have to detoxify deformed
red blood cells throughout their lifespan. Hence, their molecular equipment for detoxifying the
mess is already established when the malarial parasite attacks. Sickle-cell disease is prevalent in
malaria-stricken areas like Africa. However, individuals who don’t live in these parts still
develop the disease. Sickle-cell disease is inherited, and although it’s prevalent in Africa, any
person in the world can still have that condition if he/she inherited from one or both of the
parents (Elguero, et al. 2015).
2. Your patient with chronic lung disease has just been diagnosed with secondary
polycythemia. She asks you to explain this disease in a language she can understand
since she has no medical background. What would you say to her?
Polycythemia refers to a condition that occurs due to an increase in the volume of the red
blood cell. This condition can be divided into two groups; secondary and primary. Typically,
secondary polycythemia arises as a response to other underlying conditions or elements that