Virus

User Generated

zlathlra128

Science

Description

Briefly describe HIV

- Structure: genectic and protein

- Replication mode and life cycle

- Pathobiology

- Mode of tranmission

- Treament

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Explanation & Answer

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Running Head: DESCRIPTION OF HIV

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Structure of HIV
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DESCRIPTION OF HIV
Description of HIV
Structure
The HIV is a small and simple virus. Its core contains Ribonucleic acid (RNA) instead of
Deoxyribonucleic acid. It has three components that are basic which include: RNA that carries
all its genetic information, an enzyme known as the reverse transcriptase that it uses to replicate
by converting its single-stranded RNA into a double-stranded DNA and a binding protein which
allows it to get into the human cell. It is composed of an outer double lipid membrane which is
usually derived from the membrane of the host. The lipid membrane is usually lined with the
matrix protein and it also has spikes of glycoprotein gp120 on the surface and transmembrane
gp41 that surrounds a protein core which is cone-shaped. These two are the mediators of the
entry of the virus into the cell of the host. P24 is usually the main protein found in the capsid and
it has two single strands of RNA. Bound to the RNA are proteins p7 and p9 which are involved
in gene expression regulation (Hughes and Richard, 2002). It also has other two enzymes, the
integrase enzyme which enables its DNA to be integrated into the chromosomal DNA of the host
and the protease enzyme which...


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