Antipsychotic Meds Table

User Generated

zvxb124

Health Medical

Moraine Valley Community College

Description

Download the Week 3 Medication Table and complete the required information using the template.

Include the following sections (detailed criteria listed below and in the grading rubric)

For each medication listed, complete the following:

Provide indication, target symptoms, potency, and affected neurotransmitters.

Include half-life and CYP 450 enzyme information.

  1. List notable side effects.

Link notable side effects to the associated pathway or neurotransmitter.

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Drug name Indication Target symptoms: state if positive or negative effect Potency (if noted. receptor occupancy if noted ) Neurotransmitter(s) affected Typical antipsychotics (conventional) Haloperidol Thioridazine Thiothixene Fluphenazine Mesoridazine Chlorpromazine Atypical antipsychotics (2nd generation) Pines Olanzapine Quetiapine Asenapine Clozapine Dones Risperidone Paliperidone Ziprasidone Iloperidne Lurasidone Two Pips and a Rip Aripiprazole Brexpiprazole Cariprazine Half-life (T1/2), metabolism (CYP 450 enzyme) Notable side effects (associate to pathway or NT)
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Explanation & Answer

Attached.

1

Drug name

Indication
Target symptoms: state if positive or negative effect
Potency (if noted. receptor occupancy if noted )
Neurotransmitter(s) affected

Typical antipsychotics (conventional)
Haloperidol
• Indication: Schizophrenia, acute psychosis,
Tourette's syndrome.
• Target Symptoms: Positive symptoms.
• Potency: High potency.
• Neurotransmitters Affected: Dopamine (D2
antagonist).

Half-life
(T1/2),
metabolism
(CYP 450
enzyme)

Notable side effects (associated with pathway or NT)

Half-life: 1437 hours.
Metabolism
(CYP 450
enzyme):
CYP3A4 and
CYP2D6.



Notable Side Effects: Extrapyramidal
symptoms (EPS) linked to dopamine
antagonism, tardive dyskinesia, and
neuroleptic malignant syndrome (NMS).

Indication: Schizophrenia.
Target Symptoms: Positive symptoms.
Potency: Low potency.
Neurotransmitters Affected: Dopamine (D2
antagonist), Serotonin. (Khanna, 2024)

Half-life: 2124 hours.
Metabolism
(CYP 450
enzyme):
CYP2D6.



Notable Side Effects: QT prolongation
(cardiac arrhythmias linked to potassium
channel blockade), sedation (histamine H1
receptor).

Thiothixene






Indication: Schizophrenia.
Target Symptoms: Positive symptoms.
Potency: High potency.
Neurotransmitters Affected: Dopamine
(D2 antagonist).

Half-life: 34
hours.
Metabolism
(CYP 450
enzyme): Not
well defined.



Notable Side Effects: EPS (dopamine
antagonism), sedation (histamine H1 receptor).

Fluphenazine





Indication: Schizophrenia.
Target Symptoms: Positive symptoms.
Potency: High potency.

Half-life: 15
hours.
Metabolism
(CYP 450



Notable Side Effects: EPS (dopamine
antagonism), prolactin elevation (dopamine
antagonism).

Thioridazin...


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