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EPI 390 Study Notes Exam I

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1/9/2018
EPI 390
EXAM 1
WEEK 1
Lecture 1
Autism
Video form newscaster- https://www.cnbc.com/2015/04/21/autism-yet-again-shown-to-have-
no-link-to-measles-vaccine.html
No Connection”
No-Dichotomist variable-Either it does or doesn’t happen
Connection-Relationship between the two variables (Exposure-outcome)
“Another Study”
Results of study she’s describing is in what we’ve been taught by another study
“very Large one (study)”
Power
Study that caused problem in the first place (between MMR(measles vaccine)
and ASD(Autism spectrum disorder) is discredited, sample size of 12 children
“yet again, no connection”
Directionally in yes, no
Exposure, outcome piece
This study has results similar to another study by saying yet again
Results are consistent with other studies
“higher risk”
more likely
“no Link”
Exposure does not match outcome
“Builds on previous studies”
Further discussion on MMR-ASD
-Low vaccine rate cause outbreak of measles-Research abundant that mmr vaccine has no
correlation with autism
-Drop of vaccinations given to children with older siblings who have ASD
- Vaccine rates dropped below 92-95%-Messes with herd immunity where the population can
no longer be considered safe from the disease
-Wakefield-Bogus study where the thought measles vaccine lead to autism came about (created
problem throughout the nation)
-“relationship”-Doesn’t talk about correlation or causality
-Criteria to use the word causality
-Has been dispelled by scientific community but not in population
How do you communicate study results to a population?
-What is relationship between what epidemiologists learn in their scientific work? How can
public health relay this to the population?

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What is good and okay for an individual? Course? Population?
Epidemiology-Study of disease and populations
A/an __________ Model for Estimating Suspected Long-Term Effects of
Prenatal Cocaine Exposure on Neurodevelopmental Functioning at the
Time of Entry Into Schooling
-Build model with exposure and an outcome.
-What is the outcome? How did kids who were progeny of women who did or did not do
cocaine do
-One variable in exposure, single outcome (Same as MMR-ASD)
-No other variables given so assumed that mother provided deficit to child- Causal pathway
-Causal Pathway-Doesn’t mean that one is causing another
-Linked, association, relationship
-If not given any other information only interpretation can be made is relationship on cocaine
and development
-Not saying cocaine has nothing to do with this, but may not be cocaine alone, may be cocaine
with some other variable(s)

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1/9/2018 EPI 390 EXAM 1 WEEK 1 Lecture 1 Autism Video form newscaster- https://www.cnbc.com/2015/04/21/autism-yet-again-shown-to-haveno-link-to-measles-vaccine.html “No Connection” • No-Dichotomist variable-Either it does or doesn’t happen • Connection-Relationship between the two variables (Exposure-outcome) “Another Study” • Results of study she’s describing is in what we’ve been taught by another study “very Large one (study)” • Power • Study that caused problem in the first place (between MMR(measles vaccine) and ASD(Autism spectrum disorder) is discredited, sample size of 12 children “yet again, no connection” • Directionally in yes, no • Exposure, outcome piece • This study has results similar to another study by saying yet again Results are consistent with other studies “higher risk” more likely “no Link” • Exposure does not match outcome “Builds on previous studies” Further discussion on MMR-ASD -Low vaccine rate cause outbreak of measles-Research abundant that mmr vaccine has no correlation with autism -Drop of vaccinations given to children with older siblings who have ASD - Vaccine rates dropped below 92-95%-Messes with herd immunity where the population can no longer be considered safe from the disease -Wakefield-Bogus study where the thought measles vaccine lead to autism came about (created problem throughout the nation) -“relationship”-Doesn’t talk about correlation or causality -Criteria to use the word ...
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