Slide 1 Specific (Adaptive) Immunity Chapter 33 Slide 2 Overview of Specific (Adaptive) Immunity  Three major functions 1. Recognize anything that is foreign (“non-self”) or shouldn’t be there 2. Respond to this foreign material  This is called the Effector response  Eliminates or renders foreign material harmless 3. Remember the foreign invader that it’s seen it before  Memory response  Upon second encounter with same pathogen immune system mounts a faster and more intense response Slide 3 Acquired Immune System Development • B and T cells initially arise in the bone marrow • B cells continue to mature there • T cells are moved to the thymus for further maturation • Both cell types go through extensive screening to avoid self-reactivity Slide 4 Types of Specific Immunity • Humoral immunity • Also called antibody- mediated immunity • Based on antibody activity • Cellular immunity • Also called cell-mediated immunity • Based on action of specific kinds of T lymphocytes Specific immune system Non-specific immune system Specific immune system Slide 5 Antigens • A substance that elicits an immune response and reacts with products of that response • Most are large, complex molecules • Can have several antigenic determinant sites (epitopes) • Region in the antigen that binds to a specific antibody or T-cell receptor Slide 6 Antigen Diversity Slide 7 Acquired Immunity  Type of specific (adaptiv ...
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