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What Happens to An Enzyme Far Beyond Optical Temperature Discussion

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ENZYME’S FUNCTION 1
What happens to an enzyme far beyond its optical temperature?
By- Preyashi Karmakar
Date-06/06/2020

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ENZYME’S FUNCTION 2
How does enzyme work?
The enzyme is a protein molecule that acts as a catalyst. The enzyme has a catalytic
site (a pocket-like structure), where it binds with the substrate molecule and changes its
chemical structure and produces a product. At the catalytic site amino acids aligned here
whose functional group of side chain or cofactor or polypeptide chain form bond with the
substrate and catalyze its chemical transformation.
The reaction can be shown with the following equation-
Where E is the enzyme, P is a product, S is a substrate, ES is the enzyme-bound
substrate, and EP is the enzyme-bound product.
There are two theories about how the enzyme works. One is lock and key theory and
another is the induced fit model. The second one is more accurate. The first one told that
substrate has such a structure that can bind the active site of the enzyme; whereas the second
one told that both enzyme and substrate change their structure such a way that both can
interact with each other with the least activation energy.
Catalyst’s job is to increase the reaction rate. The enzyme also does this but without
changing the equilibrium. It creates such an environment that makes the reaction more
energetically favorable. The favor of any reaction is determined by the biochemical free
energy change, ΔG’
0
at a pH 7.0

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ENZYME’S FUNCTION 1 What happens to an enzyme far beyond its optical temperature? By- Preyashi Karmakar Date-06/06/2020 ENZYME’S FUNCTION 2 How does enzyme work? The enzyme is a protein molecule that acts as a catalyst. The enzyme has a catalytic site (a pocket-like structure), where it binds with the substrate molecule and changes its chemical structure and produces a product. At the catalytic site amino acids aligned here whose functional group of side chain or cofactor or polypeptide chain form bond with the substrate and catalyze its chemical transformation. The reaction can be shown with the following equation- Where E is the enzyme, P is a product, S is a substrate, ES is the enzyme-bound substrate, and EP is the enzyme-bound product. There are two theories about how the enzyme works. One is lock and key theory and another is the induced fit model. The second one is more accurate. The first one told that substrate has such a structure that can bind the active site of the enzyme; whereas the second one told that both enzyme and substrate change their structure such a way that both can interact with each other with the least activation energy. Catalyst’s job is to ...
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