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Sickle Cell Anemia

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Biology
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Monroe Community College
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Running Head: SICKLE CELL ANEMIA 1
Sickle Cell Anemia
Student’s Name
Institution Affiliation
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SICKLE CELL ANEMIA 2
Introduction
Sickle cell anemia, also known as sickle cell disease, refers to an illness of the blood
triggered by inherited abnormal hemoglobin (the protein which is responsible for carrying
oxygen to all parts of the body in the red blood cells) in humans. Individuals who are believed to
have this illness contain atypical molecules of hemoglobin, commonly known as hemoglobin S,
which has the potential of distorting red blood cells to form a rigid crescent or sickle shape in
certain circumstances. In a healthy individual without sickle cell anemia, the red blood cells have
round shapes, and they are capable of moving via small blood vessels to supply body tissues with
oxygen. Studies show that the disease is usually inherited from an individual’s parents.
Moreover, it has been established that problems resulting from sickle cell anemia normally begin
to appear 5 or 6 months after birth. The sickle cells have a very short lifespan of about 10 to 20
days while the healthy red blood cells last for 90 to 120 days thereby leading to a deficiency in
the number of red blood cells in the body (a condition known as anemia which makes such
people feel tired more often). Sickle cells also tend to get stuck as they attempt to move via small
red blood cells, thereby leading to the clogging of blood, consequently affecting its flow (Yawn
et al., 2014). This results in pain and may also cause several other severe conditions including
stroke, infection as well as chest syndrome. The above attacks may occur without any warning,
and people are advised to seek medical help immediately if they get one.
According to research, most individuals who are diagnosed with this disease in the
United States of America are of African descent. However, the disorder is said to be popular with
individuals of Hispanic backgrounds. Since it has been established that the disease is hereditary,
any couple willing to have children in the future is advised to carry out a genetic test. Sickle cell
anemia has been ranked as one of the most prevalent inherited blood anemia. There are various
types of sickle cell disorders, and they include the following. HbSS is a type of sickle cell
disorder whereby these people inherit sickle cells from each parent resulting in two sickle cell
genes. This is the most common type and is widely referred to as sickle cell anemia, and
researchers have classified it as the most severe form of SCD. HbSC is another form of SCD
whereby an offspring inherit from one parent a sickle cell gene and also gets abnormal
hemoglobin known as ‘’c” from the other parent. This type is associated with milder symptoms.
HbS beta thalassemia is also a type of SCD whereby individuals with this illness receive one

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Running Head: SICKLE CELL ANEMIA 1 Sickle Cell Anemia Student’s Name Institution Affiliation Date SICKLE CELL ANEMIA 2 Introduction Sickle cell anemia, also known as sickle cell disease, refers to an illness of the blood triggered by inherited abnormal hemoglobin (the protein which is responsible for carrying oxygen to all parts of the body in the red blood cells) in humans. Individuals who are believed to have this illness contain atypical molecules of hemoglobin, commonly known as hemoglobin S, which has the potential of distorting red blood cells to form a rigid crescent or sickle shape in certain circumstances. In a healthy individual without sickle cell anemia, the red blood cells have round shapes, and they are capable of moving via small blood vessels to supply body tissues with oxygen. Studies show that the disease is usually inherited from an individual’s parents. Moreover, it has been established that problems resulting from sickle cell anemia normally begin to appear 5 or 6 months after birth. The sickle cells have a very short lifespan of about 10 to 20 days while the healthy red blood cells last for 90 to 120 days thereby leading to a deficiency in the number of red blood cells in the body (a condition known as anemia which makes such people feel tired more often). Sickle cells also tend to get stuck as they attempt to move via small red blood cells, thereby leading to the clogging of blood, consequently affecting its flow (Yawn et al., 2014). This resu ...
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