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Molecular Genetics Notes

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✓ MOLECULAR GENETICS 2 . 'm( DOGMA 's not:c:÷¥ GENES . RELATE TO PROTEINS PROTEINS → RNA → (amino (mRNA) ( DNA) acids) ORGANISATION GENE SEGMENT OF DNA ENCODING FOR RNA # LOCATION OF DNA& RNA CONSISTS OF CODING , NON CODING , REGULATORY SEQUENCES - - / DNA : NUCLEUS AND MITOCHONDRIA iE÷¥ - NON CODING CODING 3. - DNA TEMPLATE STRAND ' ' 3 -5 TRANSCRIPTION T G l l l ' DNA CONVERTED TO RNA COMPONENTS : A RNA POLYMERASE ! l i / u DNA STRAND ' a ' 5 TO FREE NUCLEOTIDES RECRUITED COMP BASE PAIRING FORM mRNA STRAND THROUGH . PYRIMIDINE Adenine - Guanine FORMATION DNA → - RNA Tura, Thymine Cytosine MRNA OF → splicing EXONS & INTRONS → mRNA excised INTRONS LEAVES ONLY EXONS THAT COMPRISE C T l ' r ' I l l " , C c l l t ! C G i A mRNA 3 MRNA STRAND ' RNA POLYMERASE SYNTHESISE 'S RNA STRAND IN EILEEN . READS TEMPLATE DNA in 3' to -5 DIRECTION fesyanfanmotf.si#Lo..on * CODING STRAND - EXCISION OF ' , p FREE NUCLEOTIDE BASES Purine G 4. SPLICE VARIANTS / ALTERNATIVE SPLICING ALTERNATIVE SPLICING DIFF → INTRONS OF MRNA THROUGH EXCISION SPLICING OF of combinations . lead to diff number . of , that arrangement & polypeptide chain acids amino exons 5. TRANSLATION FORMATION OF POLYPEPTIDE CHAIN FROM MRNA MAIN COMPONENTS ? mRNA strand o Ribosome • ① PROCESS : - Ribosome ② Aminoacyl - start ③ As Codon As binds to of end ...
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