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D Tagatose Degradation Pathway

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Chemistry
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Ryerson University
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Running head: D-TAGATOSE DEGRADATION PATHWAY 1
D-Tagatose Degradation Pathway
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D-TAGATOSE DEGRADATION PATHWAY 2
D-Tagatose Degradation Pathway.
D-tagatose is a keto-hexose, which is a D-fructose's Carbon-4 epimer and a lower calorie
natural-sugar found in milk and fruit products in small quantities (Van der Heiden, Delmarcelle
& Lebrun, 2013). D-tagatose can replace sucrose in foods because their texture, taste, and
cooking properties are the same. Because of its antihyperglycemic effect and lower glycemic
index, D-tagatose seems to make a perfect sweetener. D-tagatose degradation pathway starts with
transport across the organism's cell membrane and its phosphorylation to tagatose 1-phosphate.
According to Van der Heiden et al (2013), tag 1-p is further phosphorylated by tag 1-phosphate
kinase enzyme to tagatose 1, 6-bisphosphate, which is finally broken down by gatYZ tagatose
aldolase dihydroacetone phosphate (DHAP) and Glyceraldehyde 3-phosphate (G3P) as
illustrated below.

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Running head: D-TAGATOSE DEGRADATION PATHWAY D-Tagatose Degradation Pathway Student’s Name Institution Professor’s Name Course Date 1 D-TAGATOSE DEGRADATION PATHWAY 2 D-Tagatose Degradation Pathway. D-tagatose is a keto-hexose, which is a D-fructose's Carbon-4 epimer and a lower calorie natural-sugar found in milk and fruit products in small quantities (Van der Heiden, Delmarcelle & Lebrun, 2013). D-tagatose can replace sucrose in foods because their texture, taste, and cooking properties are the same. Because of its antihyperglycemic effect and lower glycemic index, D-tagatose seems to make a perfect sweetener. D-tagatose degradation pathway starts with transport across the organism's cell membrane and its phosphorylation to tagatose 1-phosphate. According to Van der Heiden et al (2013), tag 1-p is further phosphorylated by tag 1-phosphate kinase enzyme to tagatose 1, 6-bisphosphate, which is finally broken down by gatYZ tagatose aldolase dihydroacetone phosphate (DHAP) and Glyceraldehyde 3-phosphate (G3P) as illustrated below. D-TAGATOSE DEGRADATION PATHWAY 3 D-tagatose pathway is similar to the galactitol and lactose degradation pathway in that they all lead to the production of tagatose 1, 6-bisphosphate, which is found in the D-tagatose breakdown pathway. Van der Heiden et al. (2013) asserts that, Tagatose 1, 6-bisphosphate is cleaved to dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (G3P). Organisms Utilizing D-Tagatose Degradation Pathw ...
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