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D Tagatose Conclusion Rev

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Ryerson University
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D-tagatose Degradation Conclusion
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D-tagatose Degradation Conclusion
According to Van der Heiden et al. (2013), in the D-tagatose degradation pathway, the
groups of enzymes involved include the dehydrogenases, kinase, and aldolase. The mechanism
of action of the kinase enzyme catabolizes the tagatose through a process of phosphorylation.
Phosphorylation is a chemical process which entails adding a phosphoryl group to an organic
molecule. Through phosphorylation, molecules produced are cleaved further to give rise to two
molecules, a ketone and an aldehyde that can enter the EmbdenMeyerhofParnas (EMP)
pathway.
Figure 2: Phosphorylation mechanism by enzyme phosphate kinase (Buemann et al., 1998).
Enzymes catalyze reactions by various mechanics, including oxidation-reduction or
phosphorylation. Similarly, other enzymes, such as hexokinase, phosphorylates molecules in the
glycolysis pathway to facilitate ATP production.

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1 D-tagatose Degradation Conclusion Students name Institution affiliation Course Instructor Due date 2 D-tagatose Degradation Conclusion According to Van der Heiden et al. (2013), in the D-tagatose degradation pathway, the groups of enzymes involved include the dehydrogenases, kinase, and aldolase. The mechanism of action of the kinase enzyme catabolizes the tagatose through a process of phosphorylation. Phosphorylation is a chemical process which entails adding a phosphoryl group to an organic molecule. Through phosphorylation, molecules produced are cleaved further to give rise to two molecules, a ketone and an aldehyde that can enter the Embden–Meyerhof–Parnas (EMP) pathway. Figure 2: Phosphorylation mechanism by enzyme phosphate kinase (Buemann et al., 1998). Enzymes catalyze reactions by various mechanics, including oxidation-reduction or phosphorylation. Similarly, other enzymes, such as hexokinase, phosphorylates molecules in the glycolysis pathway to facilitate ATP production. 3 Van der Heiden et al. (2013) highlights that D-tagatose is transported into cells and intermediate of D-galactose. Currently, there is no scientific literature on the regulation of the Dtagatose pathway. According to Sellick et al. (2008), the regulation of D-galactose metabolism is made by suppressing the Gal gene expression. There is a genetic switch that occurs in three distinct states regulating galactose metabolism. These include gene repression, uninduction, and inductio ...
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