This case was written by David A. Sandmire, MD and was edited for content for use in this class.Chief Complaint: 19-year-old non-ambulatory male with pneumonia.History: James Fenlow, a 19-year old male, is immobile and hospitalized for pneumonia. He has a long history of progressive weakening of his muscles. In the first year of his life, James reached many gross motor skill milestones, such as holding his head up, rolling over, sitting, and standing, at normal times. However, he did not walk until age 16 months, and by age two, started to assume a lordotic posture (an exaggeration of the lumbar curvature of the spine) while standing but not while sitting. Over the next several years, he suffered progressive muscle weakness, most notably in the proximal musculature of the arms, pelvis, and legs. By age 9, he required orthotic braces to assist his walking, and by age 11, he was confined to a wheelchair. In his early teen years, James was still able to use eating utensils, write, and type on a keyboard, though these functions have declined over the past year. At 16, he was hospitalized with bronchitis requiring antibiotic treatment, but recovered. Throughout the years, James has had no history of muscle pain or spasm, chest pain, or irregular heartbeat. The only medications that he normally takes are calcium and fluoride supplements.Physical Examination: On examination, James appeared fatigued and short of breath. Breath sounds were reduced. His cough was very weak. Heart sounds were normal, with no murmur. Bowel sounds were normal. Musculoskeletal exam revealed a scoliotic (lateral curvature) deformity of the spine when James sat up. James suffers from a condition called Duchenne muscular dystrophy. This is a muscular disease characterized by disturbed (“dys”) growth (“trophy”) of skeletal and cardiac muscle.Guiding QuestionsAnswer the questions below and submit as a Microsoft Word document or PDF. DUE Friday by 11:59 pm.1. Why did James have a lordotic posture and later go on to develop scoliosis (Be sure to define what each of these terms refers to)? Be sure to specifically address what muscle group deficits lead to these conditions. Why did these postures become apparent at the identified times? What is another abnormal curvature of the spine?2. For each of the abnormal spinal curvatures listed above identify other circumstances in which they are likely to be seen. 3. James is prescribed calcium supplements due to his loss of bone mass. What causes this condition in this patient? Speak specifically to the loss of muscular function and how that leads to deficits in other structures at the cellular level. As the muscular system is affected as the disease progresses, what is the effect on bone mass?4. Why is James susceptible to repeated lower respiratory tract infections? Be sure to identify specific muscular deficits that contribute, as well as the conditions within the lungs that may exacerbate the situation. 5. Propose a possible treatment for the patient in this case study. How does this treatment improve conditions for the patient? Are these improvements seen at the cellular, tissue, organ or systemic level? Grading rubric5 points - Thoughtful responses to the guiding questions for the case study, including notes which show how you arrived at your responses. Your response is written in your own words. Proper citation of sources (in APA format) that support your answers must be present.3 points - Thoughtful responses to the guiding questions in your own words without the presence of cited supporting rationale.1 point - An attempt has been made, but is not complete to the 3 point or 5 point level. For example - responses do not address all aspects of the guiding questions.0 points- No attempt is made to complete this part of the assignment.