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# Lab Smelling Parkinsons disease

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Smelling Parkinson’s disease
Doug Tyson (Remixed by Will Watkins)
January 11, 2018
Introduction
1. Why should it be important to know that someone can smell Parkinson’s disease?
Smelling Parkinson’s disease can bring an opportunity to predict the onset of the
Parkinson’s disease and can provide an opportunity for early diagnosis and prompt
treatment thereby reducing the severity of morbidities and mortality associated with the
disease.
2. How many correct decisions (out of 12) would you expect Joy make if she couldn’t really
smell Parkinson’s and was just guessing?
If Joy could really smell Parkinson’s and was just guessing, even then she can guess
3. How many correct decisions (out of 12) would it take to convince you that Joy really
could smell Parkinson’s?

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If Joy could really smell Parkinson’s then she can be expected to smell at least 6 or more
out of 12 correct decisions before it can be assumed that she can really smell Parkinson’s.
SIMULATING THE EXPERIMENT
4. What claims were the researchers hoping to find evidence against? That is, what was
their prior belief (null hypothesis) about the ability to smell Parkinson’s?
Null hypothesis in this situation is that no one has the ability to guess that someone has
Parkinson’s disease by smelling their clothes.
5. What claim were the researchers hoping to find evidence for? This is called the
alternative hypothesis or the research hypothesis.
The researchers were trying to find evidence that Parkinson’s disease can be smelled
from the secretions (sweat) of the persons having Parkinson’s disease or about to have it.
This was the alternative hypothesis or the research hypothesis of the experiment.
6. Your instructor will hand you 12 cards (shirts) that have been shuffled into a random
order. Don’t turn them over yet! On the back of some of them is “Parkinson’s” and on the
back of other is “No Parkinson’s” For each card, guess Parkinson’s or no Parkinson’s and
pace your cards into two piles, one for those you guessed Parkinson’s and other one for

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Smelling Parkinson’s disease Doug Tyson (Remixed by Will Watkins) January 11, 2018 Introduction 1. Why should it be important to know that someone can smell Parkinson’s disease? Smelling Parkinson’s disease can bring an opportunity to predict the onset of the Parkinson’s disease and can provide an opportunity for early diagnosis and prompt treatment thereby reducing the severity of morbidities and mortality associated with the disease. 2. How many correct decisions (out of 12) would you expect Joy make if she couldn’t really smell Parkinson’s and was just guessing? If Joy could really smell Parkinson’s and was just guessing, even then she can guess about 5 correct decisions (50%). 3. How many correct decisions (out of 12) would it take to convince you that Joy really could smell Parkinson’s? If Joy could really smell Parkinson’s then she can be expected to smell at least 6 or more out of 12 correct decisions before it can be assumed that she can really smell Parkinson’s. SIMULATING THE EXPERIMENT 4. What claims were the researchers hoping to find evidence against? That is, what was their prior belief (null hypothesis) about the ability to smell Parkinson’s? Null hypothesis in this situation is that no one has the ability to guess that someone has Parkinson’s disease by smelling their clothes. 5. What claim were the researchers hoping to find evidence for? This is called the alternative hypothesis or the research hypothesis. The researchers ...
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