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The Egyptian Journal of Medical Human Genetics (2011) 12, 31–38 Ain Shams University The Egyptian Journal of Medical Human Genetics www.ejmhg.eg.net www.sciencedirect.com ORIGINAL ARTICLE Risk factors for autism: An Egyptian study Farida El-Baz a b c a,* , Nanees Ahmed Ismael b, Sahar M. Nour El-Din c Pediatrics Department, Ain-Shams University, Egypt Community Department, Ain-Shams University, Egypt Medical Genetics Center, Ain-Shams University, Egypt Received 14 September 2010; accepted 19 January 2011 KEYWORDS Autistic disorder; Autism; Risk factors; Perinatology; Egypt; Mental retardation Abstract This study has been conducted to determine the possible risk factors of autism. This case control study was conducted at pediatric hospital, Ain Shams University on, 100 autistic patients who were subjected to the followings tools: Confirmation of diagnosis using DSM-IV-TR criteria, IQ assessment using Stanford–Binrent intelligence scale, and assessment of severity of autistic symptoms using childhood autism rating scale (CARS). Full clinical examination, neurological examination, EEG and audiological assessment were also done. Forty-six percent of our patients with autistic symptoms presented at the age of one and half years and 32% at the age of 2 years. Fifty-five percent of our patients had mild to severe retardation (IQ = 20–70), 36% below average mentality (IQ = 71–89) and 9% with normal mentality (IQ = 90–109). High maternal age (mother, P35 years) ...
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