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IVF versus IVM

IVF versus IVM

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IVF versus IVM- What is the difference, what is right for you!

INTRODUCTION

Infertility has always been a challenge for medical science. There are a variety of causes of

infertility due to reproductive deficiencies in either sex. There was a time when an infertility

diagnosis was considered a dead end. However, with the advancement in medical sciences

and technology, assisted reproduction techniques (ARTs) were developed which was a ray of

hope for the infertile couples.

Introduced in the later part of the 1970s, In Vitro fertilization (abbreviated as IVF) is an

assisted reproduction technique with excellent results. It is based on stimulating female

ovulation process leading to the production of mature eggs which are then collected and

fertilized with sperms of the male partner outside the body in a controlled environment.

Once fertilization occurs, the fertilized egg is implanted in the uterus of the female and

pregnancy is monitored for its progress.

On the other hand, In Vitro maturation (IVM) is a new and revolutionary technique in which

immature eggs are collected from a woman’s ovary under ultrasound guidance and then

matured in the laboratory under the influence of hormones. Once the eggs are matured

they are fertilized using a technique called Intra Cytoplasmic Sperm Injection (ICSI).

DISCUSSION

IVF is a technique known for many years now with demonstrated results. It has helped a lot

of couples achieve their dream of having a baby. In order to have a deeper insight into both

forms of ARTs, let us have a look on the steps/stages involved in both the procedures.

For the sake of convenience in understanding, IVF can be divided into the following steps:

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• Follicular development

The first stage in IVF is the development of ovarian hormones inside the ovary of a

woman undergoing IVF. This is done by using hormone injections.

• Egg acquisition

Once the follicles have matured, an injection of human chorionic gonadotrophin is

administered which results in the physiological process of ovulation and the mature

eggs so obtained are recovered.

• Controlled Fertilization

The eggs obtained as a result of step 1 is subjected to sperms of the male partner in

a controlled environment in a fertility lab in a petri dish. It is observed

microscopically to ensure fertilization of the egg

• Selection of the best embryo

Embryos so obtained are studied and analyzed microscopically to identify the best

embryos with the greatest chances of survival and best characteristics.

• Embryo implantation

The final step is re introducing the embryos into the womb of the woman, who is

then thoroughly monitored for implantation and subsequent progress of the

pregnancy.

Similarly, the process of IVM can be understood and differentiated from IVF by looking at

the steps involved. They are:

Step One

This is the first and diagnostic step in which the optimal time to obtain eggs from a woman

are ascertained according to ultrasonography and hematological evidence.

Step Two

This is the surgical step in which a small operation is performed to obtain the eggs

Step Three

This is the crux of the procedure. Eggs are matured under the influence of hormones to

become viable for fertilization

Step Four

In this step, Intra cytoplasmic sperm injections (ICSI) are used to fertilize the eggs obtained

in step four.

Step Five

Again a surgical procedure is performed to obtain introduce the fertilized eggs into the

womb of candidate for IVM

These are some of the basic differences between the two techniques.

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IVF versus IVM- What is the difference, what is right for you! INTRODUCTION Infertility has always been a challenge for medical science. There are a variety of causes of infertility due to reproductive deficiencies in either sex. There was a time when an infertility diagnosis was considered a dead end. However, with the advancement in medical sciences and technology, assisted reproduction techniques (ARTs) were developed which was a ray of hope for the infertile couples. Introduced in the later part of the 1970s, In Vitro fertilization (abbreviated as IVF) is an assisted reproduction technique with excellent results. It is based on stimulating female ovulation process leading to the production of mature eggs which are then collected and fertilized with sperms of the male partner outside the body in a controlled environment. Once fertilization occurs, the fertilized egg is implanted in the uterus of the female and pregnancy is monitored for its progress. On the other hand, In Vitro maturation (IVM) is a new and revolutionary technique in which immature eggs are collected from a woman’s ovary under ultrasound guidance and then matured in the laboratory under the influence of hormo ...
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