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IVF versus IVM

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IVF versus IVM- What is the difference, what is right for you!
INTRODUCTION
Infertility has always been a challenge for medical science. There are a variety of causes of
infertility due to reproductive deficiencies in either sex. There was a time when an infertility
diagnosis was considered a dead end. However, with the advancement in medical sciences
and technology, assisted reproduction techniques (ARTs) were developed which was a ray of
hope for the infertile couples.
Introduced in the later part of the 1970s, In Vitro fertilization (abbreviated as IVF) is an
assisted reproduction technique with excellent results. It is based on stimulating female
ovulation process leading to the production of mature eggs which are then collected and
fertilized with sperms of the male partner outside the body in a controlled environment.
Once fertilization occurs, the fertilized egg is implanted in the uterus of the female and
pregnancy is monitored for its progress.
On the other hand, In Vitro maturation (IVM) is a new and revolutionary technique in which
immature eggs are collected from a woman’s ovary under ultrasound guidance and then
matured in the laboratory under the influence of hormones. Once the eggs are matured
they are fertilized using a technique called Intra Cytoplasmic Sperm Injection (ICSI).
DISCUSSION
IVF is a technique known for many years now with demonstrated results. It has helped a lot
of couples achieve their dream of having a baby. In order to have a deeper insight into both
forms of ARTs, let us have a look on the steps/stages involved in both the procedures.
For the sake of convenience in understanding, IVF can be divided into the following steps:

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Follicular development
The first stage in IVF is the development of ovarian hormones inside the ovary of a
woman undergoing IVF. This is done by using hormone injections.
Egg acquisition
Once the follicles have matured, an injection of human chorionic gonadotrophin is
administered which results in the physiological process of ovulation and the mature
eggs so obtained are recovered.
Controlled Fertilization
The eggs obtained as a result of step 1 is subjected to sperms of the male partner in
a controlled environment in a fertility lab in a petri dish. It is observed
microscopically to ensure fertilization of the egg
Selection of the best embryo
Embryos so obtained are studied and analyzed microscopically to identify the best
embryos with the greatest chances of survival and best characteristics.
Embryo implantation
The final step is re introducing the embryos into the womb of the woman, who is
then thoroughly monitored for implantation and subsequent progress of the
pregnancy.
Similarly, the process of IVM can be understood and differentiated from IVF by looking at
the steps involved. They are:
Step One
This is the first and diagnostic step in which the optimal time to obtain eggs from a woman
are ascertained according to ultrasonography and hematological evidence.
Step Two
This is the surgical step in which a small operation is performed to obtain the eggs
Step Three
This is the crux of the procedure. Eggs are matured under the influence of hormones to
become viable for fertilization
Step Four
In this step, Intra cytoplasmic sperm injections (ICSI) are used to fertilize the eggs obtained
in step four.
Step Five
Again a surgical procedure is performed to obtain introduce the fertilized eggs into the
womb of candidate for IVM
These are some of the basic differences between the two techniques.

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IVF versus IVM- What is the difference, what is right for you! INTRODUCTION Infertility has always been a challenge for medical science. There are a variety of causes of infertility due to reproductive deficiencies in either sex. There was a time when an infertility diagnosis was considered a dead end. However, with the advancement in medical sciences and technology, assisted reproduction techniques (ARTs) were developed which was a ray of hope for the infertile couples. Introduced in the later part of the 1970s, In Vitro fertilization (abbreviated as IVF) is an assisted reproduction technique with excellent results. It is based on stimulating female ovulation process leading to the production of mature eggs which are then collected and fertilized with sperms of the male partner outside the body in a controlled environment. Once fertilization occurs, the fertilized egg is implanted in the uterus of the female and pregnancy is monitored for its progress. On the other hand, In Vitro maturation (IVM) is a new and revolutionary technique in which immature eggs are collected from a woman’s ovary under ultrasound guidance and then matured in the laboratory under the influence of hormo ...
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Very useful material for studying!

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