Access Millions of academic & study documents

CORRECTED MAIN DISSERTATION

Content type
User Generated
Showing Page:
1/86
Assessment of Quality of Life of Caregivers of Epileptic Children at The Children’s
Hospital and The Institute of Child Health, Lahore
Dr Allah Rakha Roll No.653-17 MPH 1
Institute of Public Health, Lahore
Epilepsy is one of the commonly occurring neurological disorders that affect
people of all nations, all ages and all races.
1
Epilepsy is the most common
serious neurological disorder and is one of the world's most prevalent non-
communicable diseases. Epilepsy is a neurological disorder characterized by
recurrent seizures, which are sudden surges of electrical activity in the brain is
epilepsy. Epilepsy tends to arise suddenly, as it has highly changeable
character and high psychological impact.
2
Epilepsy is also classified as a “seizure disorder”. Seizures are the periods of
hyperactivity in which neurons act more rapidly than normal. Children are
more vulnerable to epilepsy.
3
Epilepsy has devastating consequences for
people's lives. Some are related to injuries and a high risk of premature death,
including sudden unexpected death associated with seizures.
4
The clinical hallmark of epilepsy is the incidence of episodes termed as
seizures which are the classic clinical manifestations; signs and symptoms as
a result of abnormal excessive or synchronous neuronal brain activity.
Epilepsy can be diagnosed if at least two unprovoked (or reflex) seizures
occur more than 24 hours apart, in case of one unprovoked (or reflex) seizure
with a high probability of recurrence or in case of a diagnosis of an epilepsy
syndrome.
5

Sign up to view the full document!

lock_open Sign Up
Showing Page:
2/86
Assessment of Quality of Life of Caregivers of Epileptic Children at The Children’s Hospital
and The Institute of Child Health, Lahore
Dr. Allah Rakha Roll No. 653-17 MPH
Institute of Public Health, Lahore
2
Most epileptic seizures occur spontaneously, or they may be triggered by
factor such as fatigue, fever or stress. In occasional epilepsy types, seizures
may be reflexively provoked by a specific recognizable precipitant such as
flashing light, a sudden noise, alcohol, hot water, or cognitive activity
(speaking, reading, and counting). Epilepsy can result from various underlying
brain disorders. Genetics is involved in a substantial part of cases of epilepsy,
either as the direct underlying cause or by modulating the susceptibility to an
epileptogenic trigger.
6
The causal contribution of genetics may either be directly, due to rare single
gene defects, or indirectly due to the interaction of multiple genes and
external factors. Structural pathology of the brain due to stroke, tumor,
trauma, infection, cortical malformation, gliosis or sclerosis (scarring of brain
tissue), is also frequently associated with epilepsy. These lesions may induce
functional changes in specific brain areas resulting in the occurrence of
seizures. In addition, metabolic abnormalities and specific syndromes (e.g.
West’s or Lennox-Gastaut’s) have been described in the etiology of epilepsy.
In many cases, however, the underlying cause of epilepsy is unknown or
poorly known, with most probably a presumed genetic, microstructural or
immunological basis.
7

Sign up to view the full document!

lock_open Sign Up
Showing Page:
3/86

Sign up to view the full document!

lock_open Sign Up
End of Preview - Want to read all 86 pages?
Access Now
Unformatted Attachment Preview
Assessment of Quality of Life of Caregivers of Epileptic Children at The Children’s Hospital and The Institute of Child Health, Lahore Epilepsy is one of the commonly occurring neurological disorders that affect people of all nations, all ages and all races.1 Epilepsy is the most common serious neurological disorder and is one of the world's most prevalent noncommunicable diseases. Epilepsy is a neurological disorder characterized by recurrent seizures, which are sudden surges of electrical activity in the brain is epilepsy. Epilepsy tends to arise suddenly, as it has highly changeable character and high psychological impact.2 Epilepsy is also classified as a “seizure disorder”. Seizures are the periods of hyperactivity in which neurons act more rapidly than normal. Children are more vulnerable to epilepsy.3 Epilepsy has devastating consequences for people's lives. Some are related to injuries and a high risk of premature death, including sudden unexpected death associated with seizures.4 The clinical hallmark of epilepsy is the incidence of episodes termed as seizures which are the classic clinical manifestations; signs and symptoms as a result of abnormal excessive or synchronous neuronal brain activity. Epilepsy can be diagnosed if at least two unprovoked (or reflex) seizures occur more than 24 hours apart, in case of one unprovoked (or reflex) seizure with a high probability of recurrence or in case of a diagnosis of an epilepsy syndrome. 5 Dr Allah Rakha Roll No. ...
Purchase document to see full attachment
User generated content is uploaded by users for the purposes of learning and should be used following Studypool's honor code & terms of service.
Studypool
4.7
Indeed
4.5
Sitejabber
4.4