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N515 Module 6 Part 5 COPD S 2021

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Respiratory Disorders: COPD Chronic Obstructive Pulmonary Disorder (COPD)  Global Initiative for Chronic Lung Disease: www.goldcopd.org  Resources and guidelines also available from the National Heart, Lung, and Blood Institute COPD is a chronic inflammatory disorder  Bronchoconstriction  Airway Inflammation  Bronchial Hyperreactivity Epidemiology of COPD  Chronic obstructive pulmonary disease (COPD) is a progressive disease characterized by airflow limitation that is not fully reversible  Is associated with an abnormal inflammatory response of the lungs to noxious particles or gases o Chronic bronchitis: Chronic productive cough for 3 months in each of two successive years, not due to other co-morbid conditions o Emphysema: abnormal and permanent enlargement of the airspaces distal to the bronchioles  Destruction of airspace walls with fibrosis  Leading cause of mortality and morbidity worldwide  Is currently the third leading cause of death in the US  Kentucky is one of the highest states with COPD at greater than 9%  Not a male-only disease!  Primary cause of COPD is cigarette smoking and contributes to 85 to 90% of the deaths  Other risks include older age, genetic predisposition, environmental exposures, and air pollution COPD Etiology  Smoking and pollutants  Host factors Pathobiology  Impaired lung growth  Accelerated decline  Lung injury  Lung and systemic inflammation Pathology  Small airway disorders and ...
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