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Paper 3 Reed et al 2014

Paper 3 Reed et al 2014

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Current Biology 24, 98–103, January 6, 2014 ª2014 Elsevier Ltd All rights reserved http://dx.doi.org/10.1016/j.cub.2013.11.025 Rickettsia Actin-Based Motility Occurs in Distinct Phases Mediated by Different Actin Nucleators Shawna C.O. Reed,1,2,4 Rebecca L. Lamason,1 Viviana I. Risca,3,5 Emma Abernathy,2 and Matthew D. Welch1,2,* 1Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA 2Microbiology Graduate Group, University of California, Berkeley, Berkeley, CA 94720, USA 3Biophysics Graduate Group, University of California, Berkeley, Berkeley, CA 94720, USA Summary Many intracellular bacterial pathogens undergo actin-based motility to promote cell-cell spread during infection [1]. For each pathogen, motility was assumed to be driven by a single actin polymerization pathway. Curiously, spotted fever group Rickettsia differ from other pathogens in possessing two actin-polymerizing proteins. RickA, an activator of the host Arp2/3 complex, was initially proposed to drive motility [2, 3]. Sca2, a mimic of host formins [4, 5], was later shown to be required for motility [6]. Whether and how their activities are coordinated has remained unclear. Here, we show that each protein directs an independent mode of Rickettsia parkeri motility at different times during infection. Early after invasion, motility is slow and meandering, generating short, curved actin tails that are enriched with Arp2/3 complex and cofilin. Early motility re ...
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Describe three barriers that have slowed down the progress of advanced practice nursing and strategies to help overcome these barriers. (Saunders, 2014)

At least 1000 words, formatted and cited in current APA style with support from at least 5 academic sources. One of the re ...

Describe three barriers that have slowed down the progress of advanced practice nursing and strategies to help overcome these barriers. (Saunders, 2014)

At least 1000 words, formatted and cited in current APA style with support from at least 5 academic sources. One of the references should be Hamric, B. A., Hanson, M. C., & Tracy, F. M., & O’Grady, T. E. (2013). Advanced Practice Nursing: An Integrative Approach (5th ed.). St. Louis, MO: Elsevier. ISBN: 9781455739806

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FASB ASC 7-4: The concept of current cost is discussed in the FASB ASC Find three references to current cost in the FASB ASC Cite and copy these references.I need help with this question. you will have to log in to http://www2.aaahq.org/ascLogin.cfm thanks

4 pages

Linda Jackson (born 15 September 1950) is a pioneer Australian fashion designer, fashion retailer and artist

Linda Jackson (born 15 September 1950) is a pioneer Australian fashionJackson was born in Melbourne bay side suburb of Bea ...

Linda Jackson (born 15 September 1950) is a pioneer Australian fashion designer, fashion retailer and artist

Linda Jackson (born 15 September 1950) is a pioneer Australian fashionJackson was born in Melbourne bay side suburb of Beaumaris. Her parents

SCC Vessels Were Designed to Worship the Ancestors Discussion

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SCC Vessels Were Designed to Worship the Ancestors Discussion

Why did vessel shapes change over time? During the change from Style III to Style IV what happened to the decoration? Is it counterintuitive that the earliest decoration looks “abstract” while the latest “representational”? How so? What can the history of bronze decoration tell us about attempts to find meanings in them? What is taotie???

Components & Contingency Planning for an Organization.

Q1. Business Continuity and Disaster Recovery Learning Objective: Describe major components of contingency planni ...

Components & Contingency Planning for an Organization.

Q1. Business Continuity and Disaster Recovery Learning Objective: Describe major components of contingency planning. Assignment Requirements Write an informational paper that includes the following. Describe business continuity planning (BCP) and disaster recovery planning (DRP).How are BCP and DRP different? When are they implemented?Discuss hot, warm, and cold sites. Why are they important? When are they called into action? Submission Requirements · Format: Microsoft Word · Font: Arial, 12-Point, Double- Space · Citation Style: APA Q2. Evaluate a Contingency Plan Learning Objective: Evaluate a Contingency Plan for a business organization or government agency. Assignment Requirements Remember, contingency planning refers to interim measures to recover IT services following an emergency or system disruption. Browse Contingency Planning Guide for Federal Information Systems (NIST SP 800-34) and review the interim contingency planning procedures developed by the Environmental Protection Agency (EPA). Evaluate the EPA's document with respect to the NIST SP 800-34.Does it appear to you that the EPA followed NIST's guidance? That is, big picture and not every detail.What are some the contingency plan controls (CPs) did the EPA address?Conclude with your opinion of following establish procedures. (e.g., benefit or drawbacks) Submission Requirements · Format: Microsoft Word · Font: Arial, 12-Point, Double- Space · Citation Style: APA · Length: 2–3 pages (plus a cover sheet)

Unit 2 individual project ITCO391

Assignment Details Assignment DescriptionAs the lead for the design team project, it is time to create your first mock-up ...

Unit 2 individual project ITCO391

Assignment Details Assignment DescriptionAs the lead for the design team project, it is time to create your first mock-up of this interface. Based off of your previously chosen organization from the Unit 1 IP, you will now begin the design. Complete the following:In a Word document of 1–2 pages, describe at least 3 interface design techniques that you will use in your interface design.Create a mock-up interface for the project.Use at least 3 user interface design techniques.Ensure that the interface can track information (e.g., name, aliases, location, nationality, product, price, picture, notes, quantity, street address, etc.). Remember that these will vary based on the organization.The screen should be able to do the following:OpenCloseMinimizeMaximizeSubmit a screenshot in Word or another application (if functional), and confirm with your instructor that the file type is acceptable if it is not a Word document.

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Describe three barriers that have slowed down the progress of advanced practice nursing and strategies to help overcome these barriers. (Saunders, 2014)

At least 1000 words, formatted and cited in current APA style with support from at least 5 academic sources. One of the re ...

Describe three barriers that have slowed down the progress of advanced practice nursing and strategies to help overcome these barriers. (Saunders, 2014)

At least 1000 words, formatted and cited in current APA style with support from at least 5 academic sources. One of the references should be Hamric, B. A., Hanson, M. C., & Tracy, F. M., & O’Grady, T. E. (2013). Advanced Practice Nursing: An Integrative Approach (5th ed.). St. Louis, MO: Elsevier. ISBN: 9781455739806

FASB ASC 7-4: The concept of current cost is discussed in the FASB ASC Find three references to current cost in the FASB A ...

FASB ASC 7-4: The concept of current cost is discussed in the FASB ASC Find three references to current cost in the FASB ASC Cite and copy these references.I need help with this question. you will have to log in to http://www2.aaahq.org/ascLogin.cfm thanks

4 pages

Linda Jackson (born 15 September 1950) is a pioneer Australian fashion designer, fashion retailer and artist

Linda Jackson (born 15 September 1950) is a pioneer Australian fashionJackson was born in Melbourne bay side suburb of Bea ...

Linda Jackson (born 15 September 1950) is a pioneer Australian fashion designer, fashion retailer and artist

Linda Jackson (born 15 September 1950) is a pioneer Australian fashionJackson was born in Melbourne bay side suburb of Beaumaris. Her parents

SCC Vessels Were Designed to Worship the Ancestors Discussion

Why did vessel shapes change over time? During the change from Style III to Style IV what happened to the decoration? Is i ...

SCC Vessels Were Designed to Worship the Ancestors Discussion

Why did vessel shapes change over time? During the change from Style III to Style IV what happened to the decoration? Is it counterintuitive that the earliest decoration looks “abstract” while the latest “representational”? How so? What can the history of bronze decoration tell us about attempts to find meanings in them? What is taotie???

Components & Contingency Planning for an Organization.

Q1. Business Continuity and Disaster Recovery Learning Objective: Describe major components of contingency planni ...

Components & Contingency Planning for an Organization.

Q1. Business Continuity and Disaster Recovery Learning Objective: Describe major components of contingency planning. Assignment Requirements Write an informational paper that includes the following. Describe business continuity planning (BCP) and disaster recovery planning (DRP).How are BCP and DRP different? When are they implemented?Discuss hot, warm, and cold sites. Why are they important? When are they called into action? Submission Requirements · Format: Microsoft Word · Font: Arial, 12-Point, Double- Space · Citation Style: APA Q2. Evaluate a Contingency Plan Learning Objective: Evaluate a Contingency Plan for a business organization or government agency. Assignment Requirements Remember, contingency planning refers to interim measures to recover IT services following an emergency or system disruption. Browse Contingency Planning Guide for Federal Information Systems (NIST SP 800-34) and review the interim contingency planning procedures developed by the Environmental Protection Agency (EPA). Evaluate the EPA's document with respect to the NIST SP 800-34.Does it appear to you that the EPA followed NIST's guidance? That is, big picture and not every detail.What are some the contingency plan controls (CPs) did the EPA address?Conclude with your opinion of following establish procedures. (e.g., benefit or drawbacks) Submission Requirements · Format: Microsoft Word · Font: Arial, 12-Point, Double- Space · Citation Style: APA · Length: 2–3 pages (plus a cover sheet)

Unit 2 individual project ITCO391

Assignment Details Assignment DescriptionAs the lead for the design team project, it is time to create your first mock-up ...

Unit 2 individual project ITCO391

Assignment Details Assignment DescriptionAs the lead for the design team project, it is time to create your first mock-up of this interface. Based off of your previously chosen organization from the Unit 1 IP, you will now begin the design. Complete the following:In a Word document of 1–2 pages, describe at least 3 interface design techniques that you will use in your interface design.Create a mock-up interface for the project.Use at least 3 user interface design techniques.Ensure that the interface can track information (e.g., name, aliases, location, nationality, product, price, picture, notes, quantity, street address, etc.). Remember that these will vary based on the organization.The screen should be able to do the following:OpenCloseMinimizeMaximizeSubmit a screenshot in Word or another application (if functional), and confirm with your instructor that the file type is acceptable if it is not a Word document.