Radiotherapy and Oncology 62 (2002) 275–281 www.elsevier.com/locate/radonline Registration accuracy and possible migration of internal fiducial gold marker implanted in prostate and liver treated with real-time tumortracking radiation therapy (RTRT) Kei Kitamura a,*, Hiroki Shirato a, Shinichi Shimizu a, Nobuo Shinohara b, Toru Harabayashi b, Tadashi Shimizu a, Yoshihisa Kodama a, Hideho Endo a, Rikiya Onimaru a, Seiko Nishioka a, Hidefumi Aoyama a, Kazuhiko Tsuchiya a, Kazuo Miyasaka a a Department of Radiology, Hokkaido University School of Medicine, North-15 West-7, Kita-ku, Sapporo 060-8638, Japan b Department of Urology, Hokkaido University School of Medicine, North-15 West-7, Kita-ku, Sapporo 060-8638, Japan Received 15 August 2001; received in revised form 16 January 2002; accepted 1 February 2002 Abstract Background and purpose: We have developed a linear accelerator synchronized with a fluoroscopic real-time tumor-tracking system to reduce errors due to setup and organ motion. In the real-time tumor-tracking radiation therapy (RTRT) system, the accuracy of tumor tracking depends on the registration of the marker’s coordinates. The registration accuracy and possible migration of the internal fiducial gold marker implanted into prostate and liver was investigated. Materials and methods: Internal fiducial gold markers were implanted in 14 patients with prostate cancer and four patients with liver tumors. Computed tomography (CT) was carried out as a part of treat ...
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