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Using the example of a drug or family of drugs commonly used within your area of practice (P-
drug) discuss the factors which influence the selection of an appropriate dose/ formulation for a
particular patient. Within your answer you should discuss
• The pharmacokinetic (PK) and pharmacodynamic (PD) properties of the medicine and how
these are altered in different disease states.
• Any clinically significant and relevant drug interactions within your scope (PK or PD), the
mechanism, the rationale and the actions you would take to manage them.
• How the consideration of the Pharmacokinetic and pharmacodynamic properties of this
drug underpin the management of patient care within your practice
• 3 key references to support the evidence base for your discussion.

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Describe the pharmacokinetic (PK - ADME) properties for your chosen drug / drug
class

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Using the example of a drug or family of drugs commonly used within your area of practice (Pdrug) discuss the factors which influence the selection of an appropriate dose/ formulation for a particular patient. Within your answer you should discuss • The pharmacokinetic (PK) and pharmacodynamic (PD) properties of the medicine and how these are altered in different disease states. • Any clinically significant and relevant drug interactions within your scope (PK or PD), the mechanism, the rationale and the actions you would take to manage them. • How the consideration of the Pharmacokinetic and pharmacodynamic properties of this drug underpin the management of patient care within your practice • 3 key references to support the evidence base for your discussion. Describe the pharmacokinetic (PK - ADME) properties for your chosen drug / drug class ……………………………………… Continued …………………………………………… Describe the pharmacodynamic (PD) properties including explaining the mechanism of action for your chosen drug / drug class ……………………………………… Continued ………………………………………… Explain how the PK and PD properties change in different patients / diseases states …………………………………… Continued ………………………………… Use patient examples to explain how the PK/PD properties underpin management of patients in your sc ...
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