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Crohn Disease Anatomy Presentation?

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Crohn's Disease Presentation June 8, 2021​ Anatomy Inflammatory bowel disease (IBD) ○ Chronic inflammation of the GI tract ○ Chrohn’s and Ulcerative Colitis ■ Crohn’s – entire digestive tract affected ■ Ulcerative colitis – only the large intestine Crohn’s Disease ○ Chronic disease ■ Causes inflammation & irritation of digestive tract ○ Entire GI – mouth to anus ○ Most common ■ distal ileum (small intestine) ■ ileum ■ cecum (beginning of the large intestine) ■ ascending right colon ● Hard to distinguish between Crohn’s and UC (when in large intestine) (Dlugasch and Story, 2021) 2 Crohn’s Disease ● Characterized by ○ Patchy areas of inflammation and ulcers and normal tissue ■ Patchy areas - Skip lesions ● Ulcers combine to form fissures separated by nodules ○ Gives intestinal wall a cobblestone appearance ○ Leads to ■ intestine wall become thick and rigid ■ Intestinal lumen narrows and become obstructed ○ Damaged wall ■ Decreased ability to ● process food ● absorb food 3 (Capriotti and Frizzell, 2016) (Dlugasch and Story, 2021) Pathophysiology ● Etiology ○ Unknown ○ Genetic, immunological, ○ ○ environmental contributions Overactive inflammation response to unknown triggers Both parents have the disease ■ 50% chance kids will have it ● Pathophysiology ○ Crohn’s disease affects all layers of ○ the intestinal lining The mucosa (lining) constantly inflamed ■ ■ Mucosa contai ...
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